Visual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation

Nassiri, Nader; Ghorbanhosseini, Saeedeh; Jafarzadehpur, Ebrahim; Kavousnezhad, Sara; Nassiri, Nariman; Sheibani, Kourosh

doi:10.2147/opth.s157501

Cited by 7 publications

(9 citation statements)

References 24 publications

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“…The results of this study were nearly or slightly less than the results reported by Nassiri et al [7] , where, 55 eyes from 29 patients with a refractive error of [−5 to −15 D] were included in the study. The average age of patients was 24.9 years with a range of 20-39 years.…”

Section: Discussioncontrasting

confidence: 67%

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Comparison between Foldable and Hard [PMMA] Iris Claw Phakic Intraocular Lens Implantation for Correction of High Myopia

Alazab

Hamed

Hafez

et al. 2021

International Journal of Medical Arts

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Background: Iris claw phakic intraocular lens [PIOL] is one of the surgical techniques used for the correction of high myopia. This procedure reduces myopia with stable refractive results and preserves the accommodation. Aim of the Work:The aim of this study is to assess the outcome of foldable and hard [PMMA] iris claw PIOL implantation as one of surgical procedures in the management of high myopic young patients. Patients and Methods: A prospective comparative study having foldable and hard [PMMA] iris claw phakic intraocular lens [PIOL] for correction of high myopia. This study includes forty eyes [40 eyes] of twenty high myopic patients [20 pt.] with refraction range of [-10.0 D to -25.0 D] without or with cylinder not more than [-2.0 D]. The patients were divided to two groups [A] and [B], each group contains twenty [20] eyes, the first 20 eyes [group A] received a concave-convex foldable iris claw PIOL and the remaining 20 eyes [group B] received a biconcave optic hard PMMA iris claw PIOL. Result: The mean postoperative SE at 6 months in group [A] was [-0.30 ± 0.10 D] within ±1.00 D of emmetropia. In group [B] it was [-0.50 ± 0.50 D] within ±1.0 D of emmetropia. The mean postoperative cylinder at 6 months was [-0.31 ± 0.10] in group [A], and [-0.51 ± 0.51] in group [B]. There was a statistically significant difference between preoperative UCVA and postoperative UCVA at 6 months were [p<0.001] in both groups. Postoperative BCVA [logMar] at 6 months was 0.11 ± 0.14 in group [A] and 0.27 ± 0.17 in group [B].Conclusion: iris-claw phakic IOL implantation is frequently used for highly myopic cases. Compared to corneal refractive surgery, phakic IOLs favorably compete for the correction of high myopia, with increasing predictability, efficacy, safety, and quality of vision.

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Section: Discussioncontrasting

confidence: 67%

“…Loss of pigment cells from the iris could also be due to excessive wall shear stress due to changes in the fluid dynamics of the anterior chamber. Secondary glaucoma is possibly caused by increasing the resistance to the flow of aqueous humor, either within the anterior chamber or at the outflow [7] .…”

Section: : [A] Baikoff Lens and [B] Nuvita Lensmentioning

confidence: 99%

Comparison between Foldable and Hard [PMMA] Iris Claw Phakic Intraocular Lens Implantation for Correction of High Myopia

Alazab

Hamed

Hafez

et al. 2021

International Journal of Medical Arts

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“…Doors et al [18] in 2012 published the results of the multicentric European prospective study of 115 eyes of 73 patients, followed 6 months with an initial SE of −7.10 (2.70), which were obtained in 99% of patients, with the UCDVA >20/40 in 74.5%. Nassiri et al [19] in 2018 in a retrospective study of 55 eyes of 29 patients followed 6 months, the UCDVA was 20/25 or better in 81.5% of the cases. The results of Hashemi et al [20,21] in a study with 53 eyes of 28 patients with sphere −10.22 ± (3.02) were that 72.2% of the eyes had 20/25 or more vision and the safety and efficacy [24][25][26][27] are coincident with our work, especially in the first and second year.…”

Section: Discussionmentioning

confidence: 91%

Artiflex foldable lens for myopia correction results of 10 years of follow-up

Luna

Ramos-López

Castaño-Fernández

et al. 2019

Eye

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The aim of this study was to evaluate the long-term efficacy and safety of the Artiflex® lens implant and to follow the evolution of the number of corneal endothelial cells over time. Design It was a retrospective study of an observational case series of patients who underwent surgery at "The INVISION Ophthalmic Hospital" (Almería, Spain) in 2007 and who were followed for 10 years. Methods Setting: Clinical practice. Study population included 53 eyes of 30 patients who underwent an Artiflex® lens implant for the correction of myopia from −4 to −14 D. Each patient included in this study had stable myopia for at least 2 years and a contraindication for corneal refractive surgery. The efficacy index was defined as the quotient between uncorrected distance visual acuity postoperative and best-corrected distance visual acuity (BCDVA) preoperative. The safety index was calculated as the quotient between BCDVA postop and BCDVA preop. Results The average efficacy and safety indices of the lenses implanted were 1.1 (SD 0.30) and 1.06 (SD 0.2) at 10 years of follow-up. In this period of time there has been a loss of 12% of the corneal endothelial cells. The postoperative complications were pigment dispersion in four eyes (7%) of four patients and decentration of phakic intraocular lens in two eyes (4%) of another two patients. Conclusions The Artiflex® foldable phakic lens could be a safe and effective long-term alternative for myopic patients in whom laser surgery was contraindicated.

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“…Concerning the Artiflex/Veriflex pIOL, a study done by Dick et al 14 to assess the ECD of 290 eyes implanted with Artiflex pIOL for two years, reported a mean EC loss of 0.05%, 1.79%, and 1.07% at six months, one, and two years respectively. In another study by Nassiri et al 15 55 eyes underwent Artiflex lens implantation for correction of myopia, there was no statistically significant change in the ECD after six months of follow-up. The opposite was reported by Jonker et al 2 They reported chronic EC loss of 10% over 5 years in eyes implanted with the Artiflex myopic pIOL.…”

Section: Discussionmentioning

confidence: 86%

<p>Three-Year Effect of Phakic Intraocular Lenses on the Corneal Endothelial Cell Density</p>

Shaaban

2020

OPTH

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Purpose: To compare the effect of three different phakic intraocular lenses (pIOLs) on the corneal endothelial cell density (ECD). Patients and Methods: This was a prospective observational cohort study that included 60 eyes (30 patients) with axial myopia of −6.50 to −22.00 diopters (D). The Verisyse anterior chamber (AC) rigid iris fixated pIOL, the Veriflex (AC) flexible iris fixated pIOL, and the Visian posterior chamber (PC) implantable collamer lens (ICL) were implanted in three equal groups of patients. The effect of the three pIOLs on the ECD was compared over a follow-up period of one week, and one, three, and six months, and one, two, and three years. Specular microscopy was done to evaluate the cornea before the surgery and throughout the study. Changes were statistically analyzed and compared. Results: In the first three postoperative months, Verisyse and Veriflex pIOLs induced almost the same amount of endothelial cells loss of 10.3% and 10.6%, respectively, while ICLs showed endothelial cells loss of 3.5%. At the end of the three-year study, Veriflex pIOLs induced the highest rate of endothelial cell loss of 25%, while Verisyse and ICL lenses showed endothelial cells loss of 15.7% and 13.4%, respectively. The main effect of time and type of lens was statistically significant (p<0.001). Conclusion: All pIOLs cause a decrease in ECD. The AC pIOLs tend to be associated with more cell loss than PC pIOLs. Surgical insult is the important factor responsible for the early endothelial cell loss, while the material from which the pIOL is made may be an important factor for the continuous corneal endothelial cell loss over a long time.

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Visual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation

Cited by 7 publications

References 24 publications

Comparison between Foldable and Hard [PMMA] Iris Claw Phakic Intraocular Lens Implantation for Correction of High Myopia

Comparison between Foldable and Hard [PMMA] Iris Claw Phakic Intraocular Lens Implantation for Correction of High Myopia

Artiflex foldable lens for myopia correction results of 10 years of follow-up

<p>Three-Year Effect of Phakic Intraocular Lenses on the Corneal Endothelial Cell Density</p>

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