Vision-related quality of life in patients with a history of congenital glaucoma

Abstract

Purpose: To assess the vision-related quality of life in adult patients with a history of primary congenital glaucoma. Methods: In a cross-sectional hospital-based study eligible patients with a history of primary congenital glaucoma aged more than 18 were recruited in the study. Patients with secondary glaucoma and monocular patients were excluded. All patients underwent a complete ophthalmologic examination. The subjects were requested to answer a Persian approved version of the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) questionnaire. Results: A total of 23 congenital glaucoma patients have enrolled in the study. The mean age was 29.22 (9.3 SD) and mean IOP was 13.82 (5.19 SD) and 15.69 (5.26 SD) in right and left eyes, respectively. The mean number of medications was 1.13 (1.25 SD) in the right and 1.30 (1.18 SD) in the left eyes. Among all scores of NEI-VFQ-25, the lowest score belonged to mental health 53.71 (29.72) and the highest score was color vision score 83.69 (20.79). We found a significant influence of visual field defect on many subscales including general health and general vision ( p = 0.007, R = +0.65) and ( p = 0.002, R = +0.71) respectively. The Mean Defect (MD) was associated with low social functioning and peripheral vision too ( p = 0.035, R = +0.53) and ( p = 0.001, R = +0.76) respectively. Age had a negative impact on the general vision subscale ( p = 0.003, R = −0.59). Conclusion: Our study showed that visual field defect was strongly associated with many subscales scores in (NEI VFQ-25) questionnaire.

The impact of childhood glaucoma on psychosocial functioning and quality of life: a review of the literature

“…The majority of studies reported possible differences in patient’s QoL and FV in relation to their VA. The results across the studies measuring VR-QoL were mostly consistent, with seven papers reporting worse QoL in cases of increasing visual field deviation [ 79 , 81 ], worse VA [ 36 , 38 , 77 – 79 , 82 ], or worse postoperative VA [ 75 ]. Though, one study found the association with VA not to be important [ 81 ].…”

“…Many of the included papers investigated associations between the main outcomes (i.e., QoL or FV) and at least one clinical, treatment, or disease-specific factor. For instance, the studies most frequently compared PF or QoL findings to glaucoma type or laterality [ 36 – 38 , 75 , 77 , 78 , 83 , 85 , 88 , 90 ], visual acuity (VA) [ 36 – 38 , 75 , 77 – 79 , 82 , 83 , 88 , 90 ], age at or duration since diagnosis [ 36 , 38 , 77 , 79 , 83 , 86 , 87 ], medication or treatment practices [ 36 , 71 , 75 , 77 – 79 , 81 – 83 , 88 ], and number and outcomes of glaucoma surgeries [ 36 , 38 , 75 , 77 – 79 , 81 – 83 , 85 – 88 ]. In relation to family and broader sociodemographic characteristics, researchers most frequently compared outcome measures to age, gender, marital status, parental education level, employment status, household income, socioeconomic status, and presence of another child with glaucoma in the family [ 36 – 38 , 75 , 77 – 79 , 81 , 83 , 85 – 88 , 90 ].…”

Ocular adverse events associated with anti-VEGF therapy: A pharmacovigilance study of the FDA adverse event reporting system (FAERS)

“…In addition, we should take caution in explaining the significant signal, as one of the complications of advanced neovascular AMD. Glaucoma is currently the leading cause of irreversible blindness worldwide (Quigley, 2006;Miraftabi et al, 2020) due to elevated intraocular pressure (Blumberg et al, 2015). Clinical ophthalmologists are also concerned about the increase of intraocular pressure after the administration of anti-VEGF drugs.…”

Methodological Principles for the Development of a Questionnaire “Quality of Life” in Patients with Computer Visual Syndrome

“…Современный этап развития офтальмологии характеризуется существенным повышением уровня практической значимости оценки «качества жизни» (КЖ) пациента, что связано с надежностью и достоверностью получаемых данных, а также наличием значимых корреляционных связей между КЖ и объективными клиническими показателями зрительной системы. К настоящему моменту опросники КЖ (общие или специальные) нашли достаточно широкое применение практически для всех актуальных видов глазной патологии [6][7][8][9][10][11][12].…”