2018
DOI: 10.1109/jstqe.2017.2770101
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Visible Raman-Shifted Fiber Lasers for Biophotonic Applications

Abstract: The efficient nonlinear conversion of Yb-doped fiber laser systems using a combination of stimulated Raman scattering and second-harmonic generation is an effective method for developing sources for biophotonic applications in the yellowgreen spectral region. In this paper, we review recent progress in the development of these sources, compare the relative benefits of differing source architectures and demonstrate STED microscopy using an exemplar source.

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Cited by 32 publications
(12 citation statements)
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References 38 publications
(40 reference statements)
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“…The depletion laser is a custom-built frequency-doubled, Ramanshifted fiber laser providing pulses of 100's ps duration at a wavelength of 560 nm. [12] The temporal profile of the pulse and repetition rate can be adjusted, for example, to optimize performance with a specific fluorophore. The pulsed excitation and depletion lasers are synchronized and beams from each laser with orthogonal polarization states are coupled into a single-mode, polarization maintaining optical fiber.…”
Section: Easyslm-stedmentioning
confidence: 99%
“…The depletion laser is a custom-built frequency-doubled, Ramanshifted fiber laser providing pulses of 100's ps duration at a wavelength of 560 nm. [12] The temporal profile of the pulse and repetition rate can be adjusted, for example, to optimize performance with a specific fluorophore. The pulsed excitation and depletion lasers are synchronized and beams from each laser with orthogonal polarization states are coupled into a single-mode, polarization maintaining optical fiber.…”
Section: Easyslm-stedmentioning
confidence: 99%
“…In recent years, our group has demonstrated such sources at 1.12 µm, 1.18 µm and 1.24 µm, which were all then subsequently frequency doubled for biophotonics imaging applications. [27][28][29][30][31] However, as we demonstrate in this work, NIR Raman fiber systems are also highly suitable for upconversion to the MIR.…”
Section: Stimulated Raman Scattering In Optical Fibersmentioning
confidence: 86%
“…[ 6–9 ] To‐date, most laser systems which combine both SRS and SFM processes make use of separate SRS and SFM nonlinear optical crystals. [ 10–15 ] RbTiOPO 4 (RTP), in addition to having a high Raman gain coefficient, also has a very high second order nonlinear optical coefficient and as such, has been used as a crystal for SFM, SRS, and stimulated polariton scattering, with each effect nonlinear process being used in isolation. [ 16,17 ] However, to the best of our knowledge, there have been no reports of the use of RTP as a combined SRS and SFG crystal (similar to what has been demonstrated using its isomorph KTiOAsO 4 (KTA)), [ 18–20 ] and this forms the focus of our work.…”
Section: Introductionmentioning
confidence: 99%