Visible Light‐Promoted Catalyst‐Free (VLCF) Scalable Synthesis of Novel Derivatives of Isoniazid and Maleimide
Safia Iqbal,
Mohd. Kamil Hussain,
Bhoomika Singh
et al.
Abstract:We have developed a Visible Light Promoted Catalyst‐Free (VLCF) approach to synthesize novel conjugates of Isoniazid and Maleimide. This method involves the formation of an electron donor‐acceptor (EDA) complex between isoniazid and maleimide the photochemical activity of this complex drives the transformation. We successfully synthesized Isoniazid‐Maleimide derivatives (3a–d) at gram scale under visible light irradiation without an additional photo catalyst and without chromatographic purification resulting i… Show more
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