Visible Light-Mediated Photoactivated Sulfur Quantum Dots as Heightened Antibacterial Agents

Abstract

The need for antimicrobial or antibacterial fabric has increased exponentially in recent past years, especially after the outbreak of the SARS-CoV-2 pandemic. Several studies have been conducted, and the primary focus is the development of simple, automated, performance efficient and cost-efficient fabric for disposable and frequent-use items such as personal protective materials. In this regard, we have explored the light-driven antibacterial activity of water-soluble Sdots for the first time. Sdots are a new class of non-metallic quantum dots of the nanosulfur family having a polymeric sulfur core. These Sdots exhibited excellent antibacterial activity by generating reactive oxygen species under sunlight or visible light. Under 6 h of sunlight irradiation, it was observed that >90% of the bacterial growth was inhibited in the presence of Sdots. Furthermore, low toxic Sdots were employed to develop antibacterial fabric for efficiently cleaning the bacterial infection. The prominent zone of inhibition of up to 9 mm was observed post 12 h incubation of Sdots treated fabric with E. coli in the presence of visible light. Furthermore, the SEM study confirmed the bactericidal effect of these Sdots-treated fabrics. Moreover, this study might help explore the photocatalytic disinfection application of Sdots in diverse locations of interest, Sdots-based photodynamic antimicrobial chemotherapy application, and provide an opportunity to develop Sdots as a visible light photocatalyst for organic transformations and other promising applications.

Iodine-Doped 3D Print Ti Alloy for Antibacterial Therapy on Orthopedic Implants

“…We conducted a preliminary study of the antibacterial mechanism of iodine-doped implants. Numerous previous studies have shown that intracellular ROS production is a key mechanism for the effective killing of invading bacteria. ,– In this study, the fluorescence intensity of DCF was used to respond to the intracellular ROS level of bacteria. As shown in Figure A, significant green fluorescence signal was observed in the 3D-Ti–I group compared with the control group.…”

Recent developments in phycosynthesis of zinc oxide nanoparticles for biomedicine and environmental applications

“…Preparation of ZnO NPs as nanofluids was done using two dispersants: (a) Polyethylene glycol (PEG), and (b) polyvinylpyrolidone (PVP). The antimicrobial effects of the NPs rise as their size decreases [89,90]. This is due to the damage caused by the NPs when they come into contact with the cell membrane, which results in the generation of reactive oxygen species (ROS) [19].…”

Carbomer Hydrogel Composed of Cu2O and Hematoporphyrin Monomethyl Ether Promotes the Healing of Infected Wounds

“…This method has a different mechanism than traditional antibiotics, which enables antibiotic resistance could be controlled in a new way . It is well-known that PDT processes advantages such as fewer side effects and localized treatment . However, the solubility of photosensitizers is poor, and it is difficult to achieve effective drug concentrations …”