Visible light-induced antibacterial and osteogenic cell proliferation properties of hydrogenated TiO₂ nanotubes/Ti foil composite

Abstract

We successfully fabricated the hydrogenated TiO2 nanotubes/Ti foil (H-TNTs/f-Ti) composite via one-step anodization and two-step annealing. H-TNTs/f-Ti composite had a higher visible light-induced photoelectric response and more hydroxyl functional groups compared with Ti foil and unmodified TiO2 nanotubes/Ti foil composite, which contributed to limiting the proliferation of Streptococcus mutans and Porphyromonas gingivalis, promoting the proliferation of MC3T3-E1 cell on the hydroxylated surface, and improving the biocompatibility with osteogenic cells. Our study provides a simple and effective method for significantly improving dental implant efficacy.

Anodic oxidation- and hydrogenation-produced TiO2 nanotubes on titanium and its effect on gingival epithelial cell adhesion ability

“…Prior studies showed that the TiO 2 nanotubes' morphological and crystalline features remained consistent after both anodic oxidation and hydrogenation treatments [12]. The hydrogenation procedure led to oxygen vacancies, enriched the surface with -OH groups, and produced a superhydrophilic surface [14,23], which consistent with the results of XPS in this study. In our study, we utilized a proven method to produce superhydrophilic TiO 2 nanotubes.…”

Researching progress on bio-reactive electrogenic materials with electrophysiological activity for enhanced bone regeneration

“…Moreover, the proliferation of MC3T3-E1 cells on the hydroxylated surface was promoted, and improved biocompatibility with osteogenic cells was observed. As shown in Figure 4B , the photocurrent produced by the photoelectric response guarantees antibacterial activity and better biocompatibility with MC3T3-E1 cells for proliferation, thus providing a simple and effective method to significantly improve dental implant efficacy ( Zhao et al, 2021 ).…”

“…(C) Diagram of the Ti-BS/HAp osteogenic differentiation mechanism under 808 nm irradiation. (D) Schematic representations of antibacterial activity for the H-TNTs/f-Ti composite under visible light irradiation ( Fu et al, 2019 ; Petty et al, 2020 ; Zhao et al, 2021 ).…”

Graphene Oxide Loaded on TiO2-Nanotube-Modified Ti Regulates the Behavior of Human Gingival Fibroblasts

“…However, some implants still fail because of poor osseointegration, bacterial infection, and poor adhesion to soft tissue [ 4 , 5 , 6 ]. Most of the current research focuses on the osteogenesis and antibacterial aspects of implants, while less attention has been paid to soft tissue sealing [ 7 , 8 , 9 ]. In fact, the long-term stability of implants is related to both osseointegration and the sealing effect of soft tissue.…”