Visible-Light-Driven α-C(sp3)–H Bond Functionalization of Glycine Derivatives
Yao Tian,
Xiubin Bu,
Yuanrui Chen
et al.
Abstract:The glycine motif is widely prevalent in bioactive peptides. Thus, the direct and precise modification of glycine derivatives has attracted significant attention over the past few decades. Among various protocols for the modification of glycine derivatives, the visible-light-driven direct α-C(sp3)–H bond functionalization of glycine derivatives has emerged as a powerful tool to achieve this objective, owing to its merits in atom economy, selectivity, reaction simplicity, and sustainability. This review summari… Show more
The glycine derivatives are prevalent structural motifs which can be easily found in many bioloactive molecules and natural isolates. Till now, chemical synthesis of hydrazino-containing glycine derivatives is mainly focusing...
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