Visible light-driven highly atom-economical divergent synthesis of substituted fluorenols and cyclopropylcarbaldehydes

Abstract

We report a visible light-promoted intramolecular radical cascade reaction to construct fluorenol and naphthalene-fused cyclopropyl carbaldehyde derivatives.

Enantioconvergent synthesis of chiral fluorenols from racemic secondary alcohols via Pd(ii)/chiral norbornene cooperative catalysis

“…17 Until now, extensive efforts have been devoted to the synthesis of racemic FOLs and a number of effective strategies have been developed. 9,18 However, only three examples of the asymmetric synthesis of FOLs have been reported, 15 a ,19 to the best of our knowledge. Thus, the development of new strategies for their asymmetric synthesis is highly desirable.…”