Visfatin; a potential novel mediator of brown adipose tissue

Pourvali-Talatappeh, Parmida; Alipoor, Elham

doi:10.1016/j.obmed.2019.100122

Cited by 5 publications

(2 citation statements)

References 26 publications

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“…We studied visfatin, adiponectin, and chemerin hormones to examine the endocrine response of the adipose tissue. Visfatin is a 52-kDa pro-inflammatory adipokine that exerts insulin-mimetic effects (Pilz et al, 2007;Bayraktar, 2018;Pourvali-Talatappeh and Alipoor, 2019). It has a protective effect on cells exposed to inflammation and oxidative stress (Rongvaux et al, 2002;Gradinaru et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Investigation of endocrine response of thyroid and intestinal and adipose tissues due to the addition of Moringa oleifera essential oil in diet for quails exposed to heat stress

Bayraktar¹,

Tekce²,

Bayraktar³

et al. 2023

Revista Brasileira De Zootecnia

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In this study, we aimed to determine the effect of Moringa oleifera essential oil (MOEO) supplementation to rations of Japanese quail (Coturnix coturnix japonica) grown under heat stress (HS) on some adipokine (visfatin, adiponectin, and chemerin), intestinal (citrulline), 3,5,3′-triiodothyronine (T3), thyroxine (T4), and thyroid-stimulation hormone (TSH) levels in the serum. For this purpose, 320 day-old male quail chicks were used. The study was conducted over 42 days, including a 7-d adaptation period and a 35-d experimental period. Eight trial groups were established, each including 10 quail: CT (control temperature, 25 ℃), MOEO 200, MOEO 400, MOEO 600, HSC (HS control), SMOEO 200, SMOEO 400, and SMOEO 600. Based on the results, a dose-dependent decrease was observed on days 21 and 42 in serum adiponectin and T3 in the stress and stress-free groups compared with the control group due to MOEO supplementation. The lowest decrease was observed in the MOEO 600 mg/kg dose group. In addition, an increase in stressed groups was observed when examining serum citrulline levels, while chemerin levels did not have a statistically significant effect. While the decrease in serum visfatin, T4, and TSH levels on the 21st day did not have a statistically significant effect, a significant effect was determined on the 42nd day. The addition of MOEO at 600 mg/kg to the ration may be beneficial in preventing intestinal damage and inflammation that may occur due to HS.

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Section: Introductionmentioning

confidence: 99%

Investigation of endocrine response of thyroid and intestinal and adipose tissues due to the addition of Moringa oleifera essential oil in diet for quails exposed to heat stress

Bayraktar¹,

Tekce²,

Bayraktar³

et al. 2023

Revista Brasileira De Zootecnia

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“…За HUGO Gene Nomenclature Committee (HGNC) офіційною номенклатурою цього адипокіну є Nampt. Вісфатинце білок з молекулярною масою 52 kDa, що складається з 500 aмінокислот [1] і синтезується переважно вісцеральною жировою тканиною [18,36]. Окрім адипоцитів відомі й інші клітини-продуценти вісфатину: імуноцити, хондроцити, епітеліальні клітини амніону [21], міобласти, гепатоцити [22] клітини жовтого тіла яєчників [33].…”

Section: результати обговоренняunclassified

Insight on Visfatin as cardiovascular dysfunction metabolic factor (literature review)

Zaichko,

Bobetska

2024

Rep. of Vinnytsia Nation. Med. Univ.

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Annotation. Visfatin is now recognized as an integral representative of adipokines – bioregulators, predominately released by adipose tissue, that play a decisive role in paracrine and systemic regulation of different organs and systems activity. Visfatin exhibits a wide range of functions as a pro-inflammatory, immunomodulatory cytokine, hormone-like substance with insulin-mimetic properties. The dysregulation of visfatin synthesis has been implicated in obesity, metabolic syndrome, type 2 diabetes, however, the role of visfatin in cardiovascular dysfunction pathogenesis under the above mentioned conditions still remains in the dark. This review aims to provide a comprehensive overview of visfatin’s role in the metabolism regulation under physiological conditions and in obesity, its impact on small signaling molecules production in cardiovascular system, unwind possible correlations with cardiovascular dysfunction, formulate potential trends and prospects of dysadipokinemia management. An information search was conducted in specialized scientific databases Scopus, Web of Science, PubMed, MEDLINE, Google Scholar with a depth of 5 years (2018-2023). Queries were made using the standardized keywords of the MeSH (Medical Subject Headings) database: visfatin (Nampt), obesity, hydrogen sulfide, homocysteine, cardiomyopathy. Publications containing the results of randomized controlled trials, meta-analyses, and original studies on the problem outlined above were selected for in-depth analysis. We assume that modulators of H2S exchange are able to correct the production of visfatin in obesity and thus prevent the development of complications from the cardiovascular system, but this issue requires further study.

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Sitagliptin mitigates oxidative stress and up-regulates mitochondrial biogenesis markers in Brown adipose tissues of high-fat diet fed obese mice through AMPK phosphorylation

et al. 2020

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Visfatin; a potential novel mediator of brown adipose tissue

Cited by 5 publications

References 26 publications

Investigation of endocrine response of thyroid and intestinal and adipose tissues due to the addition of Moringa oleifera essential oil in diet for quails exposed to heat stress

Investigation of endocrine response of thyroid and intestinal and adipose tissues due to the addition of Moringa oleifera essential oil in diet for quails exposed to heat stress

Insight on Visfatin as cardiovascular dysfunction metabolic factor (literature review)

Sitagliptin mitigates oxidative stress and up-regulates mitochondrial biogenesis markers in Brown adipose tissues of high-fat diet fed obese mice through AMPK phosphorylation

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