Viscosupplementation with Hyaluronic Acid or Polynucleotides: Results and Hypothesis for Condro-synchronization

Saggini, Raoul; Stefano, Antonio Di; F, Capogrosso; Carniel, R; K, Haidar Hassan; Rg, Bellomo

doi:10.4172/2167-0870.1000198

Cited by 1 publication

(1 citation statement)

References 16 publications

(14 reference statements)

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“…In the tendinitis involving the rotator cuff, viscosupplementation, not only protects the joint surface, but also restores the homeostasis of the chondrocytes [115]. The hypothesis that hyaluronic acid also acts on pain modulation has been investigated and Mitsui et al [116] demonstrate that hyaluronic acid inhibits not only expression of mRNA for proinflammatory cytokines, such as IL-1b, IL-6 and TNF-a, but also COX-2/PGE2 (Prostaglandin E2) production via CD44 in IL-1-stimulated subacromial-synovium fibroblasts.…”

Section: Intra-articular Injectionsmentioning

confidence: 99%

The Role of Physical Medicine and Rehabilitation in Shoulder Disorders

Saggini¹,

Carmignano²,

Cosenza³

et al. 2018

Advances in Shoulder Surgery

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Shoulder pain is a common problem and it is responsible for a high proportion of patients presenting to general practice, causing work absenteeism and claims for sickness. A lot of factors and conditions can contribute to shoulder pain. The most prevalent cause is rotator cuff tendinitis; its relevance is correlated not only to its high prevalence rate but also to the fact that is disabling, causing high direct and indirect cost in industrialized country. Other causes of shoulder pain are shoulder impingement syndrome, calcific tendonitis, frozen shoulder, etc. In this context, physical medicine and rehabilitation plays a fundamental role. The conservative approach consists of several interventions. The aim is to decrease shoulder pain and to regain shoulder function, with the goal to reduce the degree of impingement, decreasing swelling and inflammation, and to minimize the risk of further injuries. The purpose of this chapter is to give an overview about shoulder disorders and their conservative treatment by means of physical therapy.

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Section: Intra-articular Injectionsmentioning

confidence: 99%