Viscoplastic flow of functional cellular materials with use of peridynamics

Postek, Eligiusz; Nowak, Z.; Pȩcherski, R.B.

doi:10.1007/s11012-021-01383-7

Cited by 6 publications

(3 citation statements)

References 48 publications

(61 reference statements)

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“…[29,142,[344][345][346] To recapitulate the viscoelastic nature of tissues, surface electrode arrays must be similarly viscoelastic [29,347] or viscoplastic. [30,43,70,348] However, one complexity is that viscoelastic materials are often difficult to process since they have temperature-dependent behaviors. Hydrogels are one of the most common types of viscoelastic materials, but in addition to having a limited range of temperature processing, they have a substantial water content and cannot undergo vacuum environments and are incompatible with harsh chemicals.…”

Section: Summary Current Challenges and Future Surface Arraysmentioning

confidence: 99%

Materials for Implantable Surface Electrode Arrays: Current Status and Future Directions

Tringides

Mooney

2022

Advanced Materials

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with the outermost layer of biological tissues, often spanning a significant surface area. Devices typically have multiple electrodes that aim to monitor and modulate cells and tissues in a minimally invasive manner, using biomaterials designed to evoke minimal inflammatory responses. Applications of Surface Electrode Arrays RecordingBecause surface electrode arrays can record a "snapshot" of the electrical activity at distinct locations, these arrays are useful to monitor the function of a tissue. Though the recordings are typically local field potentials, with electrodes that are small enough to modulate as little of a location as possible while still maintaining a sufficiently high conductivity, single units from individual cells have been reported. Clinically, these recordings are used to map the epicardial surface to identify instances, and potentially mechanisms, of chronic atrial fibrillation, [1] dysfunction of ventricular tachycardia caused by congenital defects, [2] and other abnormal conduction conditions in the cardiac system. Clinical electrocorticogram (ECoG) is used to identify similar functional changes on the cortical surface of the brain, most commonly to identify epileptic focal center(s), or detect seizure activity. [3][4][5][6][7] Other functional uses of ECoG include intraoperative monitoring during tumor resection. [8] A surgeon can ask a patient to perform an activity such as a speech and then identify and avoid the active cortical regions during surgery, to avoid major disruptions to the patient quality of life. StimulationInstead of passively monitoring electrical activity, multielectrode surface arrays can provide electrical current to the underlying tissue and induce a desired excitatory or inhibitory response. The applications for stimulating surface electrode arrays are often therapeutic and include implantable pacemakers, which restore a normal cardiac rhythm by providing external and overriding cues to the cardiomyocytes responsible for establishing a sinus rhythm. [9] Pulses delivered to specific regions of the spinal cord are used to manage chronic pain, [10][11][12] and more recently as a therapy to promote neuronal plasticity in Surface electrode arrays are mainly fabricated from rigid or elastic materials, and precisely manipulated ductile metal films, which offer limited stretchability. However, the living tissues to which they are applied are nonlinear viscoelastic materials, which can undergo significant mechanical deformation in dynamic biological environments. Further, the same arrays and compositions are often repurposed for vastly different tissues rather than optimizing the materials and mechanical properties of the implant for the target application. By first characterizing the desired biological environment, and then designing a technology for a particular organ, surface electrode arrays may be more conformable, and offer better interfaces to tissues while causing less damage. Here, the various materials used in each component of a surface electrode array are first r...

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Section: Summary Current Challenges and Future Surface Arraysmentioning

confidence: 99%

Materials for Implantable Surface Electrode Arrays: Current Status and Future Directions

Tringides

Mooney

2022

Advanced Materials

View full text Add to dashboard Cite

show abstract

“…Non-classical continua are the subject of the third group of articles [9][10][11][12][13]. Sapora et al [9] deal with the typical borehole problem, modelled as a circular hole in an infinite elastic medium subjected to remote biaxial loading and/or internal pressure.…”

Section: Editorialmentioning

confidence: 99%

“…A comparison of displacement fields demonstrates the effectiveness of adopting the micropolar continuum theory for describing particle composite materials, especially for the hourglass and skew configurations, where non-symmetries and size effects play a major role. Postek et al [11] investigate the deformation of open-cell copper foams under impacts, a topic of interest in studying open-cell multifunctional structures produced by additive manufacturing, e.g., crush-resistant heat exchangers and heat capacitors. It is assumed that the skeleton material is made of oxygen-free high, conductivity copper.…”

Section: Editorialmentioning

confidence: 99%