Viscometric study on the compatibility of some water-soluble polymer–polymer mixtures

Wanchoo, R. K.; Sharma, Prachi

doi:10.1016/s0014-3057(02)00386-5

Cited by 81 publications

(41 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Comparing it with the peaks of freeze-dried crosslinked unloaded hydrogel, the 1643 cm ) of gelatin, forming the insoluble hydrogel. As studied previously, a shift at peaks of interacting groups of different polymers indicates the formed hydrogen bond or other types of bonds between the chemical or functional groups [33].…”

Section: Characterization Of Gelatin-γ-pga-based Hydrogelmentioning

confidence: 54%

Synthesis of Gelatin-γ-Polyglutamic Acid-Based Hydrogel for the In Vitro Controlled Release of Epigallocatechin Gallate (EGCG) from Camellia sinensis

et al. 2013

View full text Add to dashboard Cite

Abstract:The antioxidant property and other health benefits of the most abundant catechin, epigallocatechin gallate (EGCG), are limited because of poor stability and permeability across intestine. Protecting the EGCG from the harsh gastrointestinal tract (GIT) environment can help to increase its bioavailability following oral administration. In this study, EGCG was loaded to hydrogel prepared from ionic interaction between an optimized concentration of gelatin and γ-polyglutamic acid (γ-PGA), with ethylcarbodiimide (EDC) as the crosslinker. Physicochemical characterization of hydrogel was done using Fourier transform-infrared spectroscopy (FT-IR), differential scanning calorimetry (DSC) and scanning electron microscopy (SEM). The dependence of the swelling degree (SD) of the hydrogel to the amount of gelatin, γ-PGA, EDC, swelling time and pH was determined. A high SD of the crosslinked hydrogel was noted at pH 4.5, 6.8 OPEN ACCESSPolymers 2014, 6 40 and 9.0 compared to pH 7.4, which describes pH-responsiveness. Approximately 67% of the EGCG from the prepared solution was loaded to the hydrogel after 12 h post-loading, in which loading efficiency was related to the amount of EDC. The in vitro release profile of EGCG at pH 1.2, 6.8 and 7.4, simulating GIT conditions, resulted in different sustained release curves. Wherein, the released EGCG was not degraded instantly compared to free-EGCG at controlled temperature of 37 °C at different pH monitored against time. Therefore, this study proves the potential of pH-responsive gelatin-γ-PGA-based hydrogel as a biopolymer vehicle to deliver EGCG.

show abstract

Section: Characterization Of Gelatin-γ-pga-based Hydrogelmentioning

confidence: 54%

Synthesis of Gelatin-γ-Polyglutamic Acid-Based Hydrogel for the In Vitro Controlled Release of Epigallocatechin Gallate (EGCG) from Camellia sinensis

et al. 2013

View full text Add to dashboard Cite

show abstract

“…FTIR spectroscopy has been widely used by many researchers to study the formation of blends [31][32][33]. FTIR spectrum provides information regarding intermolecular interactions corresponding to stretching or blending vibrations of particular bands, and the positions at which these peaks appear depend directly on the force constant or band strength.…”

Section: Fourier Transform Infrared Spectroscopy Studiesmentioning

confidence: 99%

Miscibility Studies of Hydroxypropyl Cellulose/Poly(Ethylene Glycol) in Dilute Solutions and Solid State

Reddy

Prabhakar

Babu

et al. 2012

International Journal of Carbohydrate Chemistry

View full text Add to dashboard Cite

The miscibility of Hydroxypropyl cellulose (HPC)/poly(ethylene glycol) (PEG) blends over an extended range of concentrations in water. The viscosity, ultrasonic velocity, and refractive index of the above blend solutions have been measured at 30• C. The interaction parameters such as Δβ and μ proposed by Chee and α proposed by Sun have been obtained using the viscosity data to probe the miscibility of the polymer blends. The values indicated that the blends were miscible when HPC content is more than 40% in the blend. The obtained results have been confirmed by the ultrasonic velocity and refractive index studies. The films of the blends were prepared by solution casting method using water as a solvent. The prepared films have been characterized by analytical techniques such as FTIR, DSC, X-RD, and SEM to probe the miscibility of HPC/PEG blends. The compatibility in the above compositions may be due to the formation of H-bonding between hydroxyl groups of HPC and etheric oxygen atom of PEG molecules.

show abstract

“…The relative viscosities of both homopolymers and blends were measured at five different temperatures (25,30,35,40, and 45°C) by using Ubbelohde type capillary viscometer. Viscosity measurements were carried out in a constant temperature water bath.…”

Section: Viscosity Measurementsmentioning

confidence: 99%

“…[23][24][25] FTIR spectrum provides information regarding intermolecular interaction via analysis of FTIR spectra corresponding to stretching or bending vibrations of particular bonds, and the positions at which these peaks appear depends directly on the force constant or bond strength. Hydrogen bonding or other secondary interactions between chemical groups on the dissimilar polymers should theoretically cause a shift in peak position of the participating groups.…”

Section: Ftir Spectroscopy Analysismentioning

confidence: 99%

Miscibility of dextran and poly(ethylene glycol) in dilute aqueous solutions. II. Effect of temperature and composition

Barsbay

Güner

2006

J of Applied Polymer Sci

View full text Add to dashboard Cite

ABSTRACT:The miscibility of dextran (Dx) with poly-(ethylene glycol) (PEG) was investigated in dilute aqueous solutions by viscometry. Homopolymers of Dx and PEG and their blends with Dx/PEG ratios of 10/90, 25/75, 50/50, 75/25, and 90/10 were studied at 25, 30, 35, 40, and 45°C in bidistilled and deionized water. Starting with the classical Huggins equation, the results of the viscosity behavior of each parent polymer and their blends were interpreted in terms of miscibility parameters, ⌬k, ⌬b, ␣, ␤, ⌬B, and . On the basis of the sign convention involved in these criteria, miscibility between Dx and PEG was found to increase with the weight fraction of PEG in the blend composition and temperature. The fourier transform infrared (FTIR) analysis is also used to investigate the miscibility of the polymer pairs. The existence of specific interactions between Dx and PEG was demonstrated by FTIR spectroscopy.

show abstract

Viscometric study on the compatibility of some water-soluble polymer–polymer mixtures

Cited by 81 publications

References 11 publications

Synthesis of Gelatin-γ-Polyglutamic Acid-Based Hydrogel for the In Vitro Controlled Release of Epigallocatechin Gallate (EGCG) from Camellia sinensis

Synthesis of Gelatin-γ-Polyglutamic Acid-Based Hydrogel for the In Vitro Controlled Release of Epigallocatechin Gallate (EGCG) from Camellia sinensis

Miscibility Studies of Hydroxypropyl Cellulose/Poly(Ethylene Glycol) in Dilute Solutions and Solid State

Miscibility of dextran and poly(ethylene glycol) in dilute aqueous solutions. II. Effect of temperature and composition

Contact Info

Product

Resources

About