Viscoelastic mechanical measurement of the healthy and atherosclerotic human coronary arteries using DIC technique

The Effect of Intraocular Pressure Load Boundary on the Biomechanics of the Human Conventional Aqueous Outflow Pathway

“…To date, experimental [ 38 , 39 , 40 ] and numerical [ 40 , 41 ] TM biomechanics studies have been limited to using isotropic elastic and hyperelastic mechanical properties to model the TM, and yet soft biological tissues are generally both anisotropic and viscoelastic [ 42 , 43 , 44 , 45 , 46 , 47 ]. Elastic materials restore the specimen to its initial configuration by releasing stored energy from loading.…”

Viscoelastic Biomechanical Properties of the Conventional Aqueous Outflow Pathway Tissues in Healthy and Glaucoma Human Eyes

“…It is known that soft biological tissues [ 62 , 63 , 64 , 65 , 66 , 67 ], especially the TM [ 36 , 58 ], are anisotropic and viscoelastic. Characterizing the time-dependent mechanical behavior of the outflow tissues with a dynamic load boundary may contribute to our understanding of active IOP regulation in the human eye [ 17 ].…”

“…To date, experimental [ 54 , 59 , 60 ] and numerical [ 60 , 61 ] TM biomechanical studies have all been limited to the isotropic elastic and hyperelastic mechanical properties of the TM, while it is known that soft biological tissues [ 62 , 63 , 64 , 65 , 66 , 67 ], especially the TM [ 36 , 58 ], are anisotropic and viscoelastic. In our prior study, we calculated the viscoelastic mechanical properties of the TM/JCT/SC complex with embedded elastic cable elements [ 68 ] using an inverse finite element (FE) method coupled with an optimization algorithm and high resolution optical coherence tomography (HR-OCT) imaging data [ 69 ].…”

Monitoring the Progression of Early Atherosclerosis Using a Fluorescence Nanoprobe for the Detection and Imaging of Phosphorylation and Glucose Levels

“…Atherosclerosis (AS) is the root cause of vascular disease worldwide, leading to myocardial infarction, angina pectoris, ischemic heart disease, ischemic stroke and other cardiovascular diseases (CVD). [1] It is one of the common clinical diseases and seriously threatens human health. The formation of AS is the results of the combined action of many factors.…”