The deformability of articular cartilage was studied in vitro in 64 bovine, canine and human joints with an indenting compressometer. Two factors contributed to the depth of the indentation: the thickness of the cartilage and its intrinsic elasticity. Within a given species, there was in general a consistent curvilinear relationship between the magnitude of the deformation and the thickness of the articular cartilage under a given level of static loading (usually 106 pounds per square inch). Although it was not possible to establish a satisfactory Young's modulus, differences in intrinsic elasticity were demonstrated by variations in the indentations produced in cartilages of comparable thickness, when subjected to the same compressive stress. These species differences corresponded roughly to variations in the water content of the articular cartilages (bovine, 87; canine, 80; human, 79%). The data are consistent with the hypothesis that deformability of articular cartilage serves to increase the congruence of joints and thereby reduce the stresses on their surfaces. A frequently postulated senescent thinning of articular cartilage received no support from measurements of 28 intact human patellas through the fifth decade of life.The functional significance of the thickness of articular cartilage was explored in a previous study (1). N o support was found for older views that it is related to compressive stress, at least of the static type. The elbow and ankle of the several species examined had thinner cartilages than other joints: they also were more congruent and had fewer degrees of freedom of motion. This suggested the possibility that articular cartilage is thicker in regions of low con-
gruence-a thesis proposed in 1891 byBraune and Fischer (2). Conceivably, because the cartilage is a deformable material, the greater thickness might serve to redistribute and thereby reduce stress at high points on.rhe underlying joint cortex (Fig 1). The present study was undertaken to see what the relationship between the thickness and deformability might be. An attempt was made to discriminate between the effect of thickness per se and the intrinsic elasticity of the tissue.
MATERIALS AND METHODS Specimen MaterialTo study articular cartilages covering a wide range of thickness (25 to 4.0 mm), 64 joints of different species were tested: proximal tibia, dog: