Visceral leishmaniasis and pregnancy: analysis of cases reported in a central-western region of Brazil

Abstract

At present, amphotericin B and its derivatives appear to be the best therapeutic option for the mother-child binomial.

New challenges in the epidemiology and treatment of visceral leishmaniasis in periurban areas

“…No note was made of recurrence or treatment failures in the women who were treated for VL. Figueiro-Filho et al [2008] described a case series of five women treated for VL during pregnancy, four with ambisome and one with antimony for VL detected post-delivery died of hemorrhage post-delivery. No relapses in women or VL in delivered babies were reported.…”

Kala-azar in Pregnancy in Mymensingh, Bangladesh: A Social Autopsy

“…Clinical decision making in kala-azar in pregnancy is difficult; treatment can harm the unborn baby, but a decision to withhold treatment can lead to vertical transmission of Leishmania [15] and also harm the pregnant mother. Also, late diagnosis of kala-azar during pregnancy can cause maternal consequences, including severe anaemia [15], [16], as occurred in the case we have reported.…”

Unusual presentation of cutaneous Leishmaniasis in pregnancy: A case report

“…Treatment of pregnant CL patients is a debated issue [19][20][21], since there is no description of congenital infection, and many antileishmanial drugs, such as pentavalent antimony or miltefosine, are teratogenic [21,22]. Consequently, alternative therapies should be evaluated in order to warrant safety and efficacy in this group of patients.…”