Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort

Oliveira, Paula Duarte de; Wehrmeister, Fernando César; Horta, Bernardo Lessa; Pérez‐Padilla, Rogelio; França, Giovanny Vinícius Araújo de; Gigante, Denise Petrucci; Barros, Fernando C.; Ong, Kenneth; Rolfe, Emanuella De Lucia

doi:10.1186/s12890-017-0510-7

Cited by 14 publications

(10 citation statements)

References 34 publications

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“…The effects of obesity on pulmonary function are more associated with FVC than with FEV 1 [37]. Furthermore, VFA is positively correlated with intra-abdominal visceral fat volume [38], with numerous studies examining the relationship between FVC and FEV 1 (VFA, FVC, and FEV 1 showed negative correlations) [25,[39][40][41]. Values are the median and the 25 th and 75 th percentiles.…”

Section: Discussionmentioning

confidence: 99%

Relationships between body composition and pulmonary function in a community-dwelling population in Japan

et al. 2020

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Pulmonary diseases, including chronic obstructive pulmonary disease (COPD), are major chronic diseases that result in decreased pulmonary function. Relationships between body composition and pulmonary function have been reported. However, few epidemiological studies have used the visceral fat area (VFA) to measure body composition. This study aimed to examine the relationship between body composition and pulmonary function. A cross-sectional study was conducted between 2015 and 2016, using data obtained from 1,287 residents aged between 19 and 91 years living in the Iwaki area of Hirosaki City, a rural region in Aomori Prefecture, Japan. Pulmonary function was evaluated using the forced vital capacity (FVC) as a percentage of the predicted value (predicted FVC%) and the ratio of forced expiratory volume in one second (FEV1) to FVC. The measurements for evaluating body composition included the body fat percentage (BFP) of the whole body and trunk, skeletal muscle index (SMI), body mass index (BMI), VFA, waist circumference (WC) at the navel level, and waist-to-hip ratio (WHR). To adjust for potential confounders, Spearman’s partial correlation analysis was used to examine the relationship between the measurements of body composition and pulmonary function. There were significant correlations between the predicted FVC% and the following parameters: BFP (whole body and trunk) in younger males; SMI in older males; WC, VFA, BMI, and SMI in younger females; and BFP (whole body and trunk) and VFA in older females. Contrastingly, WC and VFA in younger males and WC in younger females were correlated with the FEV1/FVC ratio. VFA was correlated with the FEV1/FVC ratio in younger males and predicted FVC% in older females. These findings suggest that visceral fat accumulation may increase the development of obstructive pulmonary disease in young males and accelerate the decline of pulmonary function (predicted FVC%) in older females.

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Section: Discussionmentioning

confidence: 99%

Relationships between body composition and pulmonary function in a community-dwelling population in Japan

et al. 2020

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“…Furthermore, intrathoracic fat volumes positively correlated with visceral abdominal fat volumes (26) and were inversely associated with lung function (27,28). Although the impact of increases in intrathoracic fat is less known, considering its anatomical proximity to the lung, intrathoracic fat could have a more significant effect on lung function as compared with pericardial fat.…”

Section: Discussionmentioning

confidence: 99%

Association between thoracic fat measured using computed tomography and lung function in a population without respiratory diseases

et al. 2019

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Background: Local fat distribution patterns and their local or systemic effects have recently attracted significant attention. The aim of this study was to assess the impact of thoracic adiposity on lung function in a population without respiratory diseases according to sex. Methods: A total of 455 subjects (282 males and 173 females), who had undergone spirometry, and chest and abdominal computed tomography between June 2012 and June 2016 at medical healthcare center, were included. Pericardial fat, intrathoracic fat, subcutaneous thoracic fat, and both visceral and subcutaneous abdominal fat were measured by directly assessing tissue volume using computed tomography. Multiple linear regression analyses adjusted for pack-years of smoking, high-density lipoprotein, and high-sensitivity C-reactive protein were performed to evaluate the association between fat volumes and lung function. Results: In males, intrathoracic fat and visceral abdominal fat were inversely associated with forced expiratory volume in 1 s (FEV 1 ) % predicted (P=0.025, P=0.010, respectively), and subcutaneous thoracic fat volumes showed a negative correlation with both FEV 1 % and forced vital capacity (FVC) % predicted (P=0.019, P=0.045, respectively). In females, subcutaneous thoracic fat demonstrated a negative correlation with both FEV 1 % and FVC % predicted (P=0.031 and P=0.008, respectively). Conclusions: The influence of local thoracic fat distribution on lung function differed according to sex. Visceral fat and subcutaneous thoracic fat in males and subcutaneous fat in females were significantly associated with decreased lung function.

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“…As well as a meta-analysis of the association between WC and lung function were proven (18). Visceral adipose tissue is inversely associated with FEV1 (Forced Expiratory Volume in one second) and FVC (Forced Vital Capacity) in both genders (19). Fat-Free Mass (FFM) also shows a positive relationship with pulmonary function (20).…”

Section: Introductionmentioning

confidence: 95%

Association Between Body Composition with Pulmonary Function Tests

Pouragha

Kazemi

Pouryaghoub

et al. 2020

Preprint

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Background: Why is bodyweight not a predictor of lung function, however, height, sex, race, and age are predictors of lung capacity and function. In this study, we want to investigate the association between body composition and pulmonary function. And as much as possible, answer the question of why bodyweight is not predictive of lung function.Method: This cross-sectional study was performed among 2967 employees of Tehran University of Medical Sciences (TUMS) who participated in the TUMS Employees Cohort (TEC) study. The body composition of the participants was measured using the Bioelectrical Impedance Analysis (BIA) method. Anthropometric variables were also measured as a confounder. The pulmonary function of participants was assessed by a forced spirometry test.Results: The correlation of BIA values including fat-free mass and total body water with a pulmonary function such as FEV1, FVC, and FEF25-75 is higher than most anthropometric values such as weight, wrist circumference, and the waist to hip ratio. Also, in regression analysis, age and sex had an association with pulmonary function, but the weight did not show a significant relationship. On the other hand, fat-free mass and visceral fat were significantly associated with pulmonary function. One is direct and the other is inverse.Conclusion: The hypothesis that the results of this study created in the minds of the authors were that; The direct association of fat-free mass with pulmonary function may be ineffective by the inverse association of visceral fat with pulmonary function, leading to a lack of association between weight and pulmonary function.

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Visceral and subcutaneous abdominal adiposity and pulmonary function in 30-year-old adults: a cross-sectional analysis nested in a birth cohort

Cited by 14 publications

References 34 publications

Relationships between body composition and pulmonary function in a community-dwelling population in Japan

Relationships between body composition and pulmonary function in a community-dwelling population in Japan

Association between thoracic fat measured using computed tomography and lung function in a population without respiratory diseases

Association Between Body Composition with Pulmonary Function Tests

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