Visceral adiposity index and risks of cardiovascular events and mortality in prevalent hemodialysis patients

Chen, Hung Yuan; Chiu, Yen‐Ling; Chuang, Yi Fang; Hsu, Shih Ping; Pai, Mei Fen; Yang, Ju‐Yeh; Yu, Peng

doi:10.1186/s12933-014-0136-5

Cited by 43 publications

(25 citation statements)

References 40 publications

(70 reference statements)

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“…In our multivariate and Cox regression results, VAI predicted a higher risk of composite outcomes, CV outcomes and mortality. Similar results were reported in former studies [36].…”

Section: Discussionsupporting

confidence: 93%

Central obesity and risks of cardiovascular events and mortality in prevalent hemodialysis patients

et al. 2017

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“…In our multivariate and Cox regression results, VAI predicted a higher risk of composite outcomes, CV outcomes and mortality. Similar results were reported in former studies [36].…”

Section: Discussionsupporting

confidence: 93%

Central obesity and risks of cardiovascular events and mortality in prevalent hemodialysis patients

et al. 2017

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“…Regarding the VAI, several studies have demonstrated its usefulness in measuring of visceral fat [23,30], prediction of metabolic syndrome [31] and arterial stiffness [32], and as risk marker to cardiometabolic diseases [25,30,33–35,36]. Elisha et al [37], analyzing 99 overweight women in the postmenopausal period, observed that the VAI was a weak predictor to change of visceral fat percentage after a weight loss program for six months.…”

Section: Discussionmentioning

confidence: 99%

Association between anthropometric indicators of adiposity and hypertension in a Brazilian population: Baependi Heart Study

et al. 2017

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BackgroundRecently, some studies have evaluated the role of adiposity measures in the prediction of hypertension risk, but the results are conflicting. Thus, the aim of this study was to compare which of the four indicators of adiposity (waist circumference–WC, body mass index–BMI, body adiposity index–BAI, and visceral adiposity index–VAI) were better associated with hypertension in a Brazilian population.Methods and findingsFor this study, were selected 1627 individuals (both genders, and aged over 18 years) resident in the municipality of Baependi, a city located in the Southeast of Brazil. WC, BMI, BAI and VAI were determined according to a standard protocol. Hypertension was defined as mean systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg, and/or antihypertensive drug use. The indicators of adiposity WC, BMI, BAI, and VAI were higher in hypertensive when compared to non-hypertensive individuals. In addition, WC and BMI were most strongly associated with hypertension in men and women, respectively. The area under the curve (AUC) of WC was significantly higher than VAI in men. In women, both AUC of BMI and WC showed higher discriminatory power to predict hypertension than BAI and VAI.ConclusionsThe indicators of adiposity WC and BMI were better associated with hypertension than BAI and VAI, in both genders, and it could be a useful tools for the screening of hypertensive patients.

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“…VAI is a marker of visceral adipose dysfunction and is strongly associated with cardiovascular events and type 2 diabetes (12,30,31). VAI is significantly correlated with inflammation and insulin resistance in patients with type 2 diabetes and cardiovascular disorders (12,32).…”

Section: Vai and Tg/hdl Ratio In Hypogonadismmentioning

confidence: 99%

Visceral adiposity index and triglyceride/high-density lipoprotein cholesterol ratio in hypogonadism

Haymana

Sönmez

Aydoğdu

et al. 2017

Arch. Endocrinol. Metab.

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Background: Cardiometabolic risk is high in patients with hypogonadism. Visceral adiposity index (VAI) and triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio are the practical markers of atherosclerosis and insulin resistance and independent predictors of cardiaovascular risk. To date, no study has evaluated VAI levels and TG/HDL-C ratio in hypogonadism. Subjects and methods: A total of 112 patients with congenital hypogonadotrophic hypogonadism (CHH) (mean age, 21.7 ± 2.06 years) and 124 healthy subjects (mean age, 21.5 ± 1.27 years) were enrolled. The demographic parameters, VAI, TG/HDL-C ratio, asymmetric dimethylarginine (ADMA), high-sensitivity C-reactive protein (hs-CRP), and homeostatic model assessment of insulin resistance (HOMA-IR) levels were measured for all participants. Results: The patients had higher total cholesterol (p = 0.04), waist circumference, triglycerides, insulin, and HOMA-IR levels (p = 0.001 for all) than the healthy subjects. VAI and ADMA and TG/HDL-C levels were also higher in patients than in healthy subjects (p < 0.001 for all). VAI was weakly correlated with ADMA (r = 0.27, p = 0.015), HOMA-IR (r = 0.22, p = 0.006), hs-CRP (r = 0.19, p = 0.04), and total testosterone (r = −0.21, p = 0.009) levels, whereas TG/HDL-C ratio was weakly correlated weakly with ADMA (r = 0.30, p = 0.003), HOMA-IR (r = 0.22, p = 0.006), and total testosterone (r = −0.16, p = 0.03) levels. Neither VAI nor TG/HDL-C ratio determined ADMA, HOMA-IR, and hs-CRP levels. Conclusions: The results of this study demonstrate that patients with hypogonadism have elevated VAI and TG/HDL-C ratio. These values are significantly correlated with the surrogate markers of endothelial dysfunction, inflammation, and insulin resistance. However, the predictive roles of VAI and TG/HDL-C ratio are not significant. Prospective follow-up studies are warranted to clarify the role of VAI and TG/HDL-C ratio in predicting cardiometabolic risk in patients with hypogonadism. Arch Endocrinol Metab. 2017;61(3):282-7.

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Visceral adiposity index and risks of cardiovascular events and mortality in prevalent hemodialysis patients

Cited by 43 publications

References 40 publications

Central obesity and risks of cardiovascular events and mortality in prevalent hemodialysis patients

Central obesity and risks of cardiovascular events and mortality in prevalent hemodialysis patients

Association between anthropometric indicators of adiposity and hypertension in a Brazilian population: Baependi Heart Study

Visceral adiposity index and triglyceride/high-density lipoprotein cholesterol ratio in hypogonadism

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