Viruses as a potential environmental trigger of type 1 diabetes mellitus (Review)
Jayra Alves Abrantes,
Jenner Veríssimo de Azevedo,
Fernando Fernandes
et al.
Abstract:The etiopathogenesis of type 1 diabetes mellitus (T1DM) is a complex multifactorial process that involves an intricate network of genetic, epigenetic, immunological, and environmental factors. Despite the advances in recent years, some aspects of the mechanisms involved in triggering the disease are still unclear. Infections with certain viruses have been suggested as possible environmental triggers for the autoimmune process that leads to selective and progressive destruction of pancreatic β-cells and insuffi… Show more
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