Virus sensor based on single-walled carbon nanotube: improved theory incorporating surface effects

Elishakoff, Isaac; Challamel, Noël; Soret, Clément; Bekel, Yannis; Gomez, Thomas

doi:10.1098/rsta.2012.0424

Cited by 15 publications

(5 citation statements)

References 23 publications

(29 reference statements)

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“…Experimental studies have reported tensile strengths for graphene ranging from 20 to 130 GPa [29], the chirality of graphene is typically described using two integers, (n, m), which represent the vector components of a translation that describes how a graphene sheet is rolled into a tube to form a carbon nanotube [30]. The chirality indices (n, m) specify the number of unit vectors along the two directions of the honeycomb lattice [31]. The chirality indices determine the diameter and the helicity of the nanotube, which in turn affect its electronic properties.…”

Section: Inter Atomic Modelling Of Slgmentioning

confidence: 99%

Bio-Nano Sensor utilizing Single-Layer Graphene for the Detection of Iridovirus

Makwana,

Patel

2024

Preprint

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Context: Graphene and its related compounds have remarkable optical, electrical, and chemical characteristics that make them suitable for biosensing. Nondestructive biological molecule identification is made possible by biosensors based on graphene and its derivatives. The field of biological sensors is expanding to meet the demand for sensitive early detection of disorders. The aim of the present investigation is to develop a sensor by analyzing the vibrational responses of single layer graphene sheets (SLGS) with attached microorganisms, specifically Iridoviridae. Graphene-based virus sensors typically rely on the interaction between the virus and the graphene surface, which lead to changes in the frequency response of graphene. This change can be measured and used to detect the presence of the virus. Its high surface-to-volume ratio and sensitivity to changes in its frequency make it a highly sensitive platform for virus detection. Methods: The atomistic finite element method (AFEM) has been used to carry out for dynamic analysis of SLG. Molecular structural analysis has been performed for single-layer graphene. Bridged and simply supported with roller support boundary conditions applied at the ends of SLG structure. Simulations have been performed to see how SLG behaves when used as sensors for biological creatures. A single-layer graphene armchair SLG (5, 5) with 50 nm length, exhibits its highest frequency vibration at 8.66 x 106 Hz, with a mass of 1.2786 Zg. In contrast, a zigzag- SLG with a (18,0) configuration has its lowest frequency vibration at 2.82 x 105 Hz, observed at a length of 10 nm. Finite Element Method (FEM) analysis is utilized to forecast the performance of single-layer graphene (SLG) biosensors under simply supported with roller support and bridged boundary conditions. This aids in comprehending the thresholds of detection and the influence of factors such as size, chirality, and boundary conditions on sensor effectiveness. These biosensors can be especially helpful in biological sciences and the medical field since they can considerably improve the treatment of patients, cancer early diagnosis, and pathogen identification when used in clinical environments. By simulating sensor behavior using FEM, researchers can reduce the need for costly and time-consuming experimental testing, speeding up the development process.

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Section: Inter Atomic Modelling Of Slgmentioning

confidence: 99%

Bio-Nano Sensor utilizing Single-Layer Graphene for the Detection of Iridovirus

Makwana,

Patel

2024

Preprint

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“… Although it has been demonstrated that one-dimensional continuum modeling based on beam theory is applicable for particular nanoscale devices (e.g., [ 9 ]), the continued miniaturization of mass-detection devices may eventually push the limits of classical modeling approaches. To address this issue, an extension of the present model to incorporate small-scale effects such as non-locality [ 14 , 16 , 47 ], surface effects [ 16 , 47 ], couple-stress effects [ 34 ], and microstructural inhomogeneity [ 34 , 35 ] should be pursued. Future work may also include a detailed exploration of back-calculation algorithms, based on the present model, for converting multi-modal frequency data to information on the position, mass, and geometry of the adsorbate.…”

Section: Summary/conclusion/outlookmentioning

confidence: 99%

“…In recent years resonant micro/nanoelectromechanical systems (MEMS/NEMS) [ 1 ] have received a great deal of attention from researchers in applications such as mass detection [ 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 ], chemical sensing [ 1 , 11 , 20 , 21 ], biosensing [ 1 , 11 , 14 , 16 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ], and atomic force microscopy (AFM) [ 36 , 37 , 38 ]. Resonant MEMS/NEMS have also been the focus of numerous studies in the sensors-related area of vibration energy harvesting, in which the objective is often to power autonomous sensing systems that are remotely deployed [ 1 , 39 , 40 , 41 , 42 ,…”

Section: Introductionmentioning

confidence: 99%

Toward Higher-Order Mass Detection: Influence of an Adsorbate’s Rotational Inertia and Eccentricity on the Resonant Response of a Bernoulli-Euler Cantilever Beam

Heinrich

Dufour

2015

Sensors

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In this paper a new theoretical model is derived, the results of which permit a detailed examination of how the resonant characteristics of a cantilever are influenced by a particle (adsorbate) attached at an arbitrary position along the beam’s length. Unlike most previous work, the particle need not be small in mass or dimension relative to the beam, and the adsorbate’s geometric characteristics are incorporated into the model via its rotational inertia and eccentricity relative to the beam axis. For the special case in which the adsorbate’s (translational) mass is indeed small, an analytical solution is obtained for the particle-induced resonant frequency shift of an arbitrary flexural mode, including the effects of rotational inertia and eccentricity. This solution is shown to possess the exact first-order behavior in the normalized particle mass and represents a generalization of analytical solutions derived by others in earlier studies. The results suggest the potential for “higher-order” nanobeam-based mass detection methods by which the multi-mode frequency response reflects not only the adsorbate’s mass but also important geometric data related to its size, shape, or orientation (i.e., the mass distribution), thus resulting in more highly discriminatory techniques for discrete-mass sensing.

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“…For thick and thin manoscale beams with an arbitrary cross section, a general model was formulated based on the Gurtin-Murdoch elasticity theory accounting for surface energy effects. [19] Elishakoff et al [20] also used an improved theory incorporating surface effects to investigate resonance frequencies of virus sensors. In addition, the classical plate theory is also extended to include the surface effects.…”

Section: Introductionmentioning

confidence: 99%

Flutter and vibration of elastically restrained nanowires under a nonconservative force

Xiao

2018

Z Angew Math Mech

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This paper investigates vibration and flutter behavior of a cantilevered nanowire under the action of a subtangential follower force. Taking the surface effects into account, we apply Hamilton principle to derive a governing equation for an elastically restrained nanobeam. A characteristic equation is obtained. Force‐frequency interaction curves are displayed to show the influence of the surface elasticity, surface stress, restraint stiffness on divergence and flutter force. Natural frequencies and divergence loads are calculated for conservative forces at the free end. For a generalized follower force with various tangency coefficients, dynamic instability of nanocantilevers is presented and flutter loads are calculated for subtangential, supertangential and tangential follower forces. Flutter loads are sensitive to translational and rotational spring stiffness and surface elasticity. Some special cases with some vanishing parameters reduce to the well‐known results.

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Virus sensor based on single-walled carbon nanotube: improved theory incorporating surface effects

Abstract: International audienc

Cited by 15 publications

References 23 publications

Bio-Nano Sensor utilizing Single-Layer Graphene for the Detection of Iridovirus

Bio-Nano Sensor utilizing Single-Layer Graphene for the Detection of Iridovirus

Toward Higher-Order Mass Detection: Influence of an Adsorbate’s Rotational Inertia and Eccentricity on the Resonant Response of a Bernoulli-Euler Cantilever Beam

Flutter and vibration of elastically restrained nanowires under a nonconservative force

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