Abstract:In combination with genetic determinants, susceptibility to autoimmune diseases such as Type 1 Diabetes (T1D) is established by various environmental factors including infection, microbial dysbiosis, antibiotic use, and vitamin D deficiency. Studies have implicated infection with certain viruses such as coxsackievirus B (CVB) to be an important cofactor associated with diabetes development and pathogenesis. Infections may be an instigating factor to alter the microbiome and this microbial change may be suffici… Show more
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