2022
DOI: 10.3147/jsfp.57.56
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Virucidal Effect of Disinfectants against Erythrocytic Inclusion Body Syndrome (EIBS) Virus <i>Piscine orthoreovirus</i> 2

Abstract: The virucidal effect of disinfectants on Piscine orthoreovirus 2 (PRV-2), a causative agent of erythrocytic inclusion body syndrome (EIBS), was assessed through challenge experiments with EIBS-naïve juvenile coho salmon Oncorhynchus kisutch. A 10-fold dilution of PRV-2 virus suspension (1.05 × 10 10 copies/mL of PRV-2 L2 RNA) was completely inactivated by 50 ppm povidone-iodine (15 min), 200 ppm sodium hypochlorite (30 s), or 40% ethanol (30 s). A 100-fold dilution of PRV-2 (1.05 × 10 9 copies/mL) was inactiva… Show more

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