Virtual Surgical Planning, 3D-Printing and Customized Bone Allograft for Acute Correction of Severe Genu Varum in Children

Alessandri, Giulia; Frizziero, Leonardo; Santi, Gian Maria; Liverani, Alfredo; Vivarelli, Leonardo; Gennaro, Giovanni Di; Antonioli, Diego; Menozzi, Grazia Chiara; Depaoli, Alessandro; Rocca, Gino; Trisolino, Giovanni

doi:10.3390/jpm12122051

Cited by 10 publications

(4 citation statements)

References 39 publications

(43 reference statements)

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“…To correct both angular deformities and leg length discrepancy, we planned a shortening osteotomy of the right femur and an opening wedge osteotomy of the left femur using a portion of the resected bone as an autograft on the contralateral side [10].…”

Section: Surgical Simulation and Planningmentioning

confidence: 99%

Side-to-Side Flipping Wedge Osteotomy: Virtual Surgical Planning Suggested an Innovative One-Stage Procedure for Aligning Both Knees in “Windswept Deformity”

Menozzi,

Depaoli,

Ramella

et al. 2023

JPM

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(1) Background: The adoption of Virtual Surgical Planning (VSP) and 3D technologies is rapidly growing within the field of orthopedic surgery, opening the door to highly innovative and individually tailored surgical techniques. We present an innovative correction approach successfully used in a child affected by “windswept deformity” of the knees. (2) Methods: We report a case involving a child diagnosed with “windswept deformity” of the knees. This condition was successfully addressed through a one-stage bilateral osteotomy of the distal femur. Notably, the wedge removed from the valgus side was flipped and employed on the varus side to achieve the correction of both knees simultaneously. The surgical technique was entirely conceptualized, simulated, and planned in a virtual environment. Customized cutting guides and bony models were produced at an in-hospital 3D printing point of care and used during the operation. (3) Results: The surgery was carried out according to the VSP, resulting in favorable outcomes. We achieved good corrections of the angular deformity with an absolute difference from the planned correction of 2° on the right side and 1° on the left side. Moreover, this precision not only improved surgical outcomes but also reduced the procedure’s duration and overall cost, highlighting the efficiency of our approach. (4) Conclusions: The integration of VSP and 3D printing into the surgical treatment of rare limb anomalies not only deepens our understanding of these deformities but also opens the door to the development of innovative, personalized, and adaptable approaches for addressing these unique conditions.

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Section: Surgical Simulation and Planningmentioning

confidence: 99%

Side-to-Side Flipping Wedge Osteotomy: Virtual Surgical Planning Suggested an Innovative One-Stage Procedure for Aligning Both Knees in “Windswept Deformity”

Menozzi,

Depaoli,

Ramella

et al. 2023

JPM

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“…When necessary, customallografts are prepared by matching the desired graft shape with the most suitable donor bone, allowing us to harness the biomechanical properties of structural allografts (Figure 8). The preparation methods for custom bone grafts have been detailed in a prior study [11,12]. The templates are then 3D printed using HT-PLA on an FDM 3D printer, following a previously described procedure, and sent to the hospital pharmacy service for steam sterilization.…”

Section: Vsp and 3d-printing Procedures At The In-hospital 3d-printin...mentioning

confidence: 99%

Section: Vsp and 3d-printing Procedures At The In-hospital 3d-printin...mentioning

confidence: 99%

Virtual Surgical Planning and Patient-Specific Instruments for Correcting Lower Limb Deformities in Pediatric Patients: Preliminary Results from the In-Office 3D Printing Point of Care

Trisolino,

Depaoli,

Menozzi

et al. 2023

JPM

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(1) Background: Virtual reality and 3D printing are transforming orthopedic surgery by enabling personalized three-dimensional (3D) models for surgical planning and Patient-Specific Instruments (PSIs). Hospitals are establishing in-house 3D printing centers to reduce costs and improve patient care. Pediatric orthopedic surgery also benefits from these technologies, enhancing the precision and personalization of treatments. This study presents preliminary results of an In-Office 3D Printing Point of Care (PoC), outlining considerations and challenges in using this program for treating lower limb deformities in pediatric patients through Virtual Surgical Planning (VSP) and 3D-printed Patient-Specific Instruments (PSIs). (2) Materials and Methods: Pediatric patients with congenital or acquired lower limb deformities undergoing surgical correction based on VSP, incorporating 3D-printed PSIs when required, were included in this study. The entire process of VSP and 3D printing at the In-Office PoC was illustrated. Data about deformity characteristics, surgical procedures, and outcomes, including the accuracy of angular correction, surgical times, and complications, were reported. (3) Results: In total, 39 bone correction procedures in 29 patients with a mean age of 11.6 ± 4.7 years (range 3.1–18.5 years) were performed according to VSP. Among them, 23 procedures were accomplished with PSIs. Surgeries with PSIs were 45 min shorter, with fewer fluoroscopy shots. Optimal correction was achieved in 37% of procedures, while the remaining cases showed under-corrections (41%) or over-corrections (22%). Major complications were observed in four patients (13.8%). (4) Conclusions: The In-Office 3D Printing Point of Care is becoming an essential tool for planning and executing complex corrections of lower limb deformities, but additional research is needed for optimizing the prediction and accuracy of the achieved corrections.

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“…Moreover, because of the technology, they result in low productivity (Raza et al, 2022) while they prove to be solid for low-cost end-use parts and small-lot production (Rouf et al, 2022). FDM printing processes have many fields of applications: biomedical (Frizziero et al, 2022a), tissue engineering, human bone repair (Alessandri et al, 2022;Alessandri et al, 2023), antibacterial, bioprinting (Chaturvedi et al, 2022), electrical conductivity (Mora et al, 2020), electromagnetic, sensor, battery, automotive (Romero et al, 2021;Frizziero et al, 2022b;Frizziero et al, 2022c;Frizziero et al, 2023), aviation, smart textile (Chakraborty and Biswas, 2020), environmental, and luminescence applications among other areas (Jandyal et al, 2022).…”

Section: Introduction To Fdm For the Realization Of Functional Partsmentioning

confidence: 99%

Design and development of a peristaltic pump for constant flow applications

Ferretti,

Pagliari,

Montalti

et al. 2023

Front. Mech. Eng.

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In wide-ranging areas, including hydraulics, biomedical, automotive, and aerospace, there is often a need to move a fluid with a constant flow rate. This is difficult to achieve with any type of pump and usually other elements are inserted to regularize the output. This study focused on the peristaltic pump because there are few studies on it and it has some interesting features, such as extreme simplicity, a small number of components, and the extreme compactness of the whole system. The first part of this study is focused on analyzing the classical geometry of the peristaltic pump to understand the origin of the discontinuity in the flow rate; the second part proposes a new geometry that mitigates the flow irregularity by more than 200%. In this way, it is possible to use it in all the sectors where a constant flow rate is required but where insulation between the fluid and the machine is required. Together with the flow study, an analysis of how the main geometric parameters affect the operation of the pump is provided, complete with explanatory graphs and tables. A prototype made through additive manufacturing technologies is also proposed.

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Virtual Surgical Planning, 3D-Printing and Customized Bone Allograft for Acute Correction of Severe Genu Varum in Children

Cited by 10 publications

References 39 publications

Side-to-Side Flipping Wedge Osteotomy: Virtual Surgical Planning Suggested an Innovative One-Stage Procedure for Aligning Both Knees in “Windswept Deformity”

Side-to-Side Flipping Wedge Osteotomy: Virtual Surgical Planning Suggested an Innovative One-Stage Procedure for Aligning Both Knees in “Windswept Deformity”

Virtual Surgical Planning and Patient-Specific Instruments for Correcting Lower Limb Deformities in Pediatric Patients: Preliminary Results from the In-Office 3D Printing Point of Care

Design and development of a peristaltic pump for constant flow applications

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