Virtual Reality and Visualization of 3D Reconstructed Medical Imaging: Learning Variations Within Detailed Human Anatomies

Gaasedelen, Erik; Deakyne, Alex J.; Mattson, Alexander R.; Mattison, Lars M.; Holm, Mikayle A.; Sanchez, Jorge D. Zhingre; Schmidt, Megan; Bateman, Michael G.; Iles, Tinen L.; Iaizzo, Paul A.

doi:10.1007/978-3-030-63092-8_14

Cited by 6 publications

(5 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, we used these reconstructed models of bifurcation stenting procedures to create a variety of enlarged 3D prints designed to better understand differences in various bifurcation techniques and their interaction with either calcifications (when present) and/or other complex associated anatomies. Furthermore, developed mixed reality educational modules can couple 3D prints and virtual reality scenes [ 16 ] that allow individuals or multiple users to “fly through” the same scenes [ 17 ] while simultaneously performing physical inspections of the detailed models [ 18 ]. In other words, these mixed reality teaching modules can be used for a multitude of educational endeavors, such as anatomical analyses, identifying clinical plaque deposition trends, assessing coronary stent designs, and/or developing computational fluid simulations (see free-access website “Atlas of Human Cardiac Anatomy” to visualize and download models and procedural videos; http://www.vhlab.umn.edu/atlas/index.shtml ).…”

Section: Discussionmentioning

confidence: 99%

Post-procedure micro-CT analyses of coronary artery stenting in left main vessels of reanimated and perfusion-fixed human hearts

Valenzuela

Iaizzo

2023

BioMed Eng OnLine

View full text Add to dashboard Cite

Background Percutaneous coronary interventions (PCIs) within left main coronary arteries are high-risk procedures that require optimization of interactions between stent(s) and diseased vessels. Optical Coherence Tomography (OCT) is a widely accepted tool that enhances physicians’ ability to assess proper stent appositions during clinical procedures. The primary aim of this study was to develop complementary post-procedure imaging methodologies to better assess and interpret outcomes of left main PCI procedures, utilizing both reanimated and perfusion-fixed human hearts. Methods PCIs were performed while obtaining OCT scans within the left main anatomies of six human hearts. Subsequently, each heart was scanned with a micro-CT scanner with optimized parameters to achieve resolutions up to 20 µm. Scans were reconstructed and imported into a DICOM segmentation software to generate computational models of implanted stents and associated coronary vessels. 2D images from OCT that were obtained during PCIs were compared to the 3D models generated from micro-CT reconstructions. In addition, the 3D models were utilized to create virtual reality scenes and enlarged 3D prints for development of “mixed reality” tools relative to bifurcation stenting within human left main coronary arteries. Results We developed reproducible methodologies for post-implant analyses of coronary artery stenting procedures. In addition, we generated high-resolution 3D computational models, with ~ 20-micron resolutions, of PCIs performed within reanimated and perfusion-fixed heart specimens. Conclusions Generated computational models of left main PCIs performed in isolated human hearts can be used to obtain detailed measurements that provide further clinical insights on procedural outcomes. The 3D models from these procedures are useful for generating virtual reality scenes and 3D prints for physician training and education.

show abstract

Section: Discussionmentioning

confidence: 99%

Post-procedure micro-CT analyses of coronary artery stenting in left main vessels of reanimated and perfusion-fixed human hearts

Valenzuela

Iaizzo

2023

BioMed Eng OnLine

View full text Add to dashboard Cite

show abstract

“…After detailed analysis of the 3D models from each PCI step, the resultant.stl files were imported into a video game design software Unity (San Francisco, CA, USA) to create virtual reality (VR) scenes with anaglyph capabilities [14,15]. We rendered each PCI step into its own scene where a user can wear a VR headset to interact with the detailed model.…”

Section: Methodsmentioning

confidence: 99%

Multimodal Imaging of a Culotte Bifurcation Procedure in the Left Main Coronary Artery of a Perfusion-Fixed Human Heart: Step-by-Step with Serial Micro-CT Analyses

Valenzuela

Iaizzo

2023

J. of Cardiovasc. Trans. Res.

Self Cite

View full text Add to dashboard Cite

Percutaneous coronary intervention can be a high-risk procedure that would benefit from optimizing device-tissue interactions between stents and coronary vessels. Using a perfusion-fixed human heart with coronary artery disease, we performed a percutaneous coronary intervention of the left main coronary artery bifurcation. This heart was perfused and multimodal imaging was utilized to view the procedure with direct visualization, fluoroscopy, and optical coherence tomography (OCT). We followed the European Bifurcation Club’s guidelines to perform a single-stent bifurcation before transitioning to a two-stent Culotte technique. After each procedural step, the heart was removed from the perfusion apparatus and transferred to a micro-CT scanner to obtain unique scans. We conducted apposition analyses of the computational 3D models from micro-CT DICOM datasets, and compared them to the results from direct visualization and commercial OCT’s Apposition Indicator software. Additional measurements of resulting coronary anatomic expansions were taken to determine the potential roles of each step in improving procedural outcomes. Graphical Abstract Micro-CT images show stent deformation during a percutaneous coronary intervention (provisional to Culotte bifurcation procedure) in an isolated diseased human heart.

show abstract

“…Many types of research cover different applications of the uses of VR in the development and facilitation of different disciplines in higher education, including its use in the medical field (Figure 1) by facilitating the learning of neuroanatomy (van Deursen et al, 2021), and converting magnetic resonance imaging and computed tomography-based images into 3D models and displaying them through VR headsets (Gaasedelen et al, 2021). On the other hand, virtual tours have become an effective way to use the Internet to visit some archaeological sites, tourism, and museums virtually.…”

Section: Virtual Reality Technologies In Educationmentioning

confidence: 99%

“…Figure 1. (a) View of the brain model in the VR environment (van Deursen et al, 2021), (b) VR model of the anterior mediastinum of a congenital thoracic model(Gaasedelen et al, 2021) …”

mentioning

confidence: 99%

Leverage Digital Transformation in Distance Learning for Maximum Students’ Engagement by Utilization of the Integrated Technologies of Digital Twin, Extended Realities, and Reinforcement Learning

Hlayel¹,

Jawad²

2023

IJCSR

View full text Add to dashboard Cite

show abstract

Virtual Reality and Visualization of 3D Reconstructed Medical Imaging: Learning Variations Within Detailed Human Anatomies

Cited by 6 publications

References 6 publications

Post-procedure micro-CT analyses of coronary artery stenting in left main vessels of reanimated and perfusion-fixed human hearts

Post-procedure micro-CT analyses of coronary artery stenting in left main vessels of reanimated and perfusion-fixed human hearts

Multimodal Imaging of a Culotte Bifurcation Procedure in the Left Main Coronary Artery of a Perfusion-Fixed Human Heart: Step-by-Step with Serial Micro-CT Analyses

Leverage Digital Transformation in Distance Learning for Maximum Students’ Engagement by Utilization of the Integrated Technologies of Digital Twin, Extended Realities, and Reinforcement Learning

Contact Info

Product

Resources

About