“…We anticipate there was a significant number of undiagnosed cases (e.g. PCR tests underestimating true transmission [ 3 ]), during the peak of the Omicron wave, due to the overwhelming demand for testing, which inundated the established diagnostic PCR testing systems and created a shortage of rapid antigen tests. Furthermore, half of the reported COVID-19 cases were being counted from positive rapid antigen tests ( Fig 1 ), which were not able to be sequenced.…”