2019
DOI: 10.1186/s12879-019-3674-3
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Viral species richness and composition in young children with loose or watery stool in Ethiopia

Abstract: BackgroundStool consistency is an important diagnostic criterion in both research and clinical medicine and is often used to define diarrheal disease.MethodsWe examine the pediatric enteric virome across stool consistencies to evaluate differences in richness and community composition using fecal samples collected from children aged 0 to 5 years participating in a clinical trial in the Amhara region of Ethiopia. The consistency of each sample was graded according to the modified Bristol Stool Form Scale for ch… Show more

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Cited by 20 publications
(27 citation statements)
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References 46 publications
(39 reference statements)
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“…The richness of eukaryotic virus species found in this work was higher than in previous studies in healthy children, in which less than 9 different virus species were found per individual samples [5,7,41,43,45]. We identified on average 15 (±9 s.d.)…”
Section: Discussioncontrasting
confidence: 78%
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“…The richness of eukaryotic virus species found in this work was higher than in previous studies in healthy children, in which less than 9 different virus species were found per individual samples [5,7,41,43,45]. We identified on average 15 (±9 s.d.)…”
Section: Discussioncontrasting
confidence: 78%
“…virus species per sample, which is higher even when compared to previous reports in rural or small village communities [41,43,45]. In general, we also identified a greater number of enteric viruses compared to previous studies carried out not only in healthy infants, but also in sick children [32,45]. Several factors may influence these results and should be considered in future studies.…”
Section: Discussionsupporting
confidence: 55%
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“…The results showed that rotavirus was the primary (40%) virus causing diarrhoea among children in Kuwait [33,34]. Concerning norovirus, other studies have also demonstrated that norovirus GII is the predominant genogroup known to cause gastroenteritis in children [35][36][37][38].…”
Section: Discussionmentioning
confidence: 94%