“Viral” myocarditis in a patient following allogenic stem cell transplant: Diagnostic dilemma and management considerations

Bhattacharya, Sanjay; Paneesha, Shankara; Chaganti, Sridhar; Lovell, Richard; Slocombe, G. W.; Milligan, Donald; Osman, Husam

doi:10.1016/j.jcv.2009.05.005

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“…However, allo-SCT recipients have multiple factors that may lead to myocarditis, including a high risk of viral infection and allogeneic immune reactions. Therefore, the management of myocarditis in allo-SCT recipients is thought to be more complicated and difficult than in nontransplant patients (8).…”

Section: Introductionmentioning

confidence: 99%

Myocarditis with Advanced Atrioventricular Block after Allogeneic Stem Cell Transplantation: A Case Report and Literature Review

et al. 2020

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A 51-year-old woman with Philadelphia chromosome-positive acute lymphoblastic leukemia underwent a second cord blood transplantation followed by maintenance therapy with interferon-α. After 33 months, she developed cardiogenic shock caused by advanced atrioventricular block. Laboratory tests revealed increased myocardium enzymes, and ultrasonic cardiography demonstrated mild thickening of the left ventricular wall. She was diagnosed with myocarditis and successfully treated using prednisolone. Myocarditis after allogeneic stem cell transplantation is a rare but potentially fatal complication. However, it is important for physicians to be aware of this complication because all of the symptoms may be reversed with immunosuppressive treatment.

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Section: Introductionmentioning

confidence: 99%