Viral infections of oral cavity

Santosh, Arvind Babu Rajendra; Muddana, Keerthi

doi:10.4103/jfmpc.jfmpc_807_19

Cited by 61 publications

(64 citation statements)

References 51 publications

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“…Further research is necessary to determine the diagnostic and pathological significance of oral manifestations during COVID-19. Indeed, oral mucosa involvement during viral infection may assume differing clinical significance: it could represent either the first sign of viral disease or coexist as a co-symptom or represent a unique sign of the viral infection ( 26 ). In this context, the importance of the clinical oral examination of patients with confirmed or suspicious COVID-19 infection should be emphasized, given the need for support, pain control, and quality of life.…”

Section: Discussionmentioning

confidence: 99%

Association of Viral Infections With Oral Cavity Lesions: Role of SARS-CoV-2 Infection

et al. 2021

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Different viral agents, such as herpesviruses, human papillomavirus, and Coxsackie virus, are responsible for primary oral lesions, while other viruses, such as human immunodeficiency virus, affect the oral cavity due to immune system weakness. Interestingly, it has been reported that coronavirus disease 2019 (COVID-19) patients can show cutaneous manifestations, including the oral cavity. However, the association between oral injuries and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is still unclear. This narrative review aimed to summarize the available literature and provide an overview of oral lesions associated with COVID-19. An online literature search was conducted to select relevant studies published up to November 2020. The results of 17 studies showed variability in oral lesions associated with COVID-19, including ulcerations, aphthous-like lesions, and macules. The tongue, lips, and palate were the most frequent anatomical locations. According to current knowledge, the etiopathogenesis of multiple COVID-19-associated lesions seems to be multifactorial. The appearance of such lesions could be related to the direct or indirect action of SARS-CoV-2 over the oral mucosa cells, coinfections, immunity impairment, and adverse drug reactions. Nevertheless, COVID-19-associated oral lesions may be underreported, mainly due to lockdown periods and the lack of mandatory dispositive protection. Consequently, further research is necessary to determine the diagnostic and pathological significance of oral manifestations of COVID-19. All medical doctors, dentists, and dermatologists are encouraged to perform an accurate and thorough oral examination of all suspected and confirmed COVID-19 cases to recognize the disease's possible early manifestations.

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Section: Discussionmentioning

confidence: 99%

Association of Viral Infections With Oral Cavity Lesions: Role of SARS-CoV-2 Infection

et al. 2021

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“…Viral diseases found in the mouth affect the oral tissues, which contributes to the formation of mouth ulcers in the shape of single or multiple blisters. This occurs due to cellular damage that results from reduced immunity caused by viral proteins (Santosh & Muddana, 2020). Generally speaking, viral oral infections can trigger the formation of mouth ulcers in the oral mucosa, and these ulcers have been identified as a common symptom of viral infection (Clarkson et al, 2017).…”

Section: Discussionmentioning

confidence: 99%

Oral Manifestation COVID-19 and the Rapid Resolution of Symptoms Post-Phtalox Treatment: a Case Series

Orcina

Santos

2021

Int. J. Odontostomat.

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The mouth plays a critical role in the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) owing to the fact that both the tongue and salivary glands are conducive environments for the storage and spread of the virus. This case series aimed to describe the oral manifestations of coronavirus disease (COVID-19) and report the rapid response to Phtalox® treatment in all patients who tested positive for the virus. The patients were grouped based on whether according to convenience as soon as they tested positive for COVID-19. All patients had mouth ulcers and were advised to use 5 mL of Phtalox® mouthwash for 1 min, five times daily, in addition to standard COVID-19 treatment. Complete healing of mouth ulcers occurred in all patients diagnosed with COVID-19, and the mean duration for complete healing was 2.37 days. General improvement of COVID-19 symptoms was also observed. Based on the rapid recovery of mouth ulcers observed, we suggest that Phtalox® is effective as a complementary oral treatment for ulcers associated with COVID-19.

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“…In this context, when health professionals, especially dentists, are faced with enanthema in oral mucosa as a possible diagnostic challenge in the COVID‐19 pandemic, it is important to review some of the main viral diseases associated with oral enanthema, as illustrated in Table 1 (Castro & Ramos‐e‐Silva, 2020; Drago et al., 2017; Santosh & Muddana, 2020; Scully & Samaranayake, 2016). Such action is especially relevant in tropical countries such as Brazil, where other viral diseases are in endemic transmission.…”

Section: Viral Disease Etiology Oral Enanthema Additional Signs and mentioning

confidence: 99%

Viral enanthema in oral mucosa: A possible diagnostic challenge in the COVID‐19 pandemic

et al. 2020

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Viral infections of oral cavity

Cited by 61 publications

References 51 publications

Association of Viral Infections With Oral Cavity Lesions: Role of SARS-CoV-2 Infection

Association of Viral Infections With Oral Cavity Lesions: Role of SARS-CoV-2 Infection

Oral Manifestation COVID-19 and the Rapid Resolution of Symptoms Post-Phtalox Treatment: a Case Series

Viral enanthema in oral mucosa: A possible diagnostic challenge in the COVID‐19 pandemic

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