2008
DOI: 10.1002/art.23883
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Viral infection and reactivation in autoimmune disease

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Cited by 27 publications
(22 citation statements)
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“…The bidirectional paradigm of autoimmunity and infections Patients with ADs have at least a twofold risk of acquiring infections compared with healthy individuals [22]. Box 1.…”
Section: Manifestation Of Autoimmune Diseases and Infectionsmentioning
confidence: 99%
“…The bidirectional paradigm of autoimmunity and infections Patients with ADs have at least a twofold risk of acquiring infections compared with healthy individuals [22]. Box 1.…”
Section: Manifestation Of Autoimmune Diseases and Infectionsmentioning
confidence: 99%
“…Several studies have shown that HZ is more common and can present with more severe manifestations among patients with systemic lupus erythematosus (SLE) [212]. Some studies suggest that the incidence may be increased in SLE even in the absence of immunosuppressive medications [3,9] and during periods of relative disease quiescence [13], possibly because of an inherent deficiency in cell mediated immunity associated with the disease process itself.…”
Section: Introductionmentioning
confidence: 99%
“…11,12 While effective at reducing inflammation, these chronic treatments have undesirable side effects and reduce overall immunity (i.e., immunosuppression), leading to increased risk for infections and cancer. 1315 Thus, novel therapeutic approaches to lupus are greatly needed. Toward this end, we began a program to target specific autoantibody populations with small-molecule “decoy antigen” compounds, thereby rendering them unavailable to bind tissue antigen.…”
Section: Introductionmentioning
confidence: 99%