Viral Disease

Macy, James D; Compton, Susan R

doi:10.1016/b978-0-12-814338-4.00013-1

Cited by 2 publications

(1 citation statement)

References 247 publications

(345 reference statements)

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“…For purification and plaque assay, L-2cells, L2P-41.a, and LBC are often used [ 100 , 101 ]. The virus samples can be stored at −60 °C for 7 years, but according to research by Jacoby et al (1975), they can become less infectious when stored at −20 °C [ 11 , 105 ].…”

Section: Characteristicsmentioning

confidence: 99%

SDAV, the Rat Coronavirus—How Much Do We Know about It in the Light of Potential Zoonoses

Bartak

Słońska

Banbura

et al. 2021

Viruses

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Sialodacryoadenitis virus (SDAV) is known to be an etiological agent, causing infections in laboratory rats. Until now, its role has only been considered in studies on respiratory and salivary gland infections. The scant literature data, consisting mainly of papers from the last century, do not sufficiently address the topic of SDAV infections. The ongoing pandemic has demonstrated, once again, the role of the Coronaviridae family as extremely dangerous etiological agents of human zoonoses. The ability of coronaviruses to cross the species barrier and change to hosts commonly found in close proximity to humans highlights the need to characterize SDAV infections. The main host of the infection is the rat, as mentioned above. Rats inhabit large urban agglomerations, carrying a vast epidemic threat. Of the 2277 existing rodent species, 217 are reservoirs for 66 zoonotic diseases caused by viruses, bacteria, fungi, and protozoa. This review provides insight into the current state of knowledge of SDAV characteristics and its likely zoonotic potential.

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Section: Characteristicsmentioning

confidence: 99%

SDAV, the Rat Coronavirus—How Much Do We Know about It in the Light of Potential Zoonoses

Bartak

Słońska

Banbura

et al. 2021

Viruses

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Screening of West Nile Virus, Herpesvirus, and Parvovirus in Rattus spp. in Klang Valley, Malaysia

Natasha¹,

Yasmin²,

Siti-Maisarah³

et al. 2022

JTAS

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Free-roaming and scavenging lifestyles of Rattus spp. in densely populated urban areas expose them to multiple pathogens that facilitate the transmission of infection to the human population more rapidly, raising public health concerns. There is limited information on the status of rat susceptibility to virus infection, particularly West Nile virus (WNV), herpesvirus, and parvovirus, to prepare for emerging zoonosis. A total of 23 (n = 23) blood samples collected from Rattus spp. in the wet market areas of Klang Valley, Malaysia, were subjected to molecular assay using a one-step reverse transcription-polymerase chain reaction (RT-PCR) to detect the highly conserved region of the WNV capsid and pre-membrane protein via nested polymerase chain reaction (PCR) assay targeting highly conserved amino acid motifs within the herpesviral DNA-directed DNA polymerase gene (DPOL) and polymerase chain reaction (PCR) assay targeting the parvovirus non-structural (NS) protein. As a result, 4 out of 23 (17.39%) rats were positive for herpesvirus DNA, but none were positive for WNV RNA and parvovirus DNA. The positive PCR amplicons of herpesvirus DNA were subjected to partial DNA sequencing analysis, 100% identical to Acomys herpesvirus SVMS 226,222 from Betaherpesvirinae, which is highly suggestive of rat cytomegalovirus (RCMV). This study has successfully demonstrated the presence of RCMV from Rattus spp. in the Klang Valley. The RCMV potentially crosses species barriers and establishes infection, raising public health concerns. The non-viraemic state of WNV or parvovirus infection, low sample size, and limited niche distribution emphasise the need for the expansion of this study in the future.

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Viral Disease

Cited by 2 publications

References 247 publications

SDAV, the Rat Coronavirus—How Much Do We Know about It in the Light of Potential Zoonoses

SDAV, the Rat Coronavirus—How Much Do We Know about It in the Light of Potential Zoonoses

Screening of West Nile Virus, Herpesvirus, and Parvovirus in Rattus spp. in Klang Valley, Malaysia

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