Viral Antibodies in Obsessive Compulsive Disorder in India

Khanna, Sumant; Ravi, V; Shenoy, Poornima K.; Chandramukhi, A; Channabasavanna, S. M.

doi:10.1097/00002826-199202001-00610

Cited by 2 publications

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“…A growing body of literature reported the occurrence of obsessions and compulsions in patients who had recently recovered from viral encephalitis 132 . Already in 1930s more than a third of cases of obsessive and compulsive disorders (OCD) were recognised an organic in pathogenesis, and linked with Von Economo's encephalitis 133 .…”

Section: Covid-19 and Obsessive-compulsive Disordermentioning

confidence: 99%

Psychiatric face of COVID-19

2020

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The Coronavirus Disease 2019 (COVID-19) represents a severe multiorgan pathology which, besides cardio-respiratory manifestations, affects the function of the central nervous system (CNS). The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), similarly to other coronaviruses demonstrate neurotropism; the viral infection of the brain stem may complicate the course of the disease through damaging central cardio-respiratory control. The systemic inflammation as well as neuroinflammatory changes are associated with massive increase of the brain proinflammatory molecules, neuroglial reactivity, altered neurochemical landscape and pathological remodelling of neuronal networks. These organic changes, emerging in concert with environmental stress caused by experiences of intensive therapy wards, pandemic fears and social restrictions, promote neuropsychiatric pathologies including major depressive disorder, bipolar disorder (BD), various psychoses, obsessive-compulsive disorder and post-traumatic stress disorder. The neuropsychiatric sequelae of COVID-19 represent serious clinical challenge that has to be considered for future complex therapies.

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Section: Covid-19 and Obsessive-compulsive Disordermentioning

confidence: 99%

Psychiatric face of COVID-19

2020

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“…They also discussed the possibility that the immunological dysfunction could be due to an unidentified infectious agent or an autoimmune process. As an extension of the hypothesis, viral antibodies were measured in the blood[ 72 ] and cerebrospinal fluid (CSF) of OCD subjects. [ 73 ] IgG viral antibodies for herpes simplex virus-1 (HSV-1), varicella zoster, cytomegalo virus, measles and mumps were studied in 76 subjects with OCD and compared with 55 normal healthy volunteers.…”

Section: Neurobiologymentioning

confidence: 99%

An overview of Indian research in obsessive compulsive disorder

Reddy

Rao

Khanna

2010

Indian J Psychiatry

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Obsessive-compulsive disorder (OCD) was considered a relatively rare disorder until about two decades ago. Since then, considerable advance has been made in understanding the various aspects of OCD that include epidemiology, clinical features, comorbidity, biology and treatment. In the last one decade, there has also been interest in a group of related disorders called obsessive-compulsive spectrum disorders. There is substantial research from India on various aspects of OCD, particularly from the National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore. We attempt to review all the relevant Indian data on OCD.

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Viral Antibodies in Obsessive Compulsive Disorder in India

Cited by 2 publications

References 0 publications

Psychiatric face of COVID-19

Psychiatric face of COVID-19

An overview of Indian research in obsessive compulsive disorder

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