“…Antisocial behavior (ASB) is characterized by a complex pattern of overt and covert hostility, often resulting in aggression toward others, property damage, and rule violations. As such, it imposes a substantial burden on society and public health (Whitehead et al, 2003;Shepherd et al, 2004), on account of the robust association of ASB with delinquency and violent crimes (Shader et al, 2003;Stone, 2007), as well as a broad spectrum of psychiatric disorders (Sher et al, 2015). Although no medications are currently approved for ASB, several drugs, including lithium, anticonvulsants, sedatives, antipsychotics, and antidepressants, are used to reduce aggression (Fava, 1997;Khalifa et al, 2010), but are often inadequate and associated to significant adverse events.…”