Vine tea (Ampelopsis grossedentata): A review of chemical composition, functional properties, and potential food applications

Carneiro, Renata; Ye, Liyun; Baek, Naerin; Teixeira, Gustavo Henrique de Almeida; O’Keefe, Sean F.

doi:10.1016/j.jff.2020.104317

Cited by 35 publications

(22 citation statements)

References 51 publications

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“…Vine tea ( Ampelopsis grossedentata ) and sweet tea ( Rubus suavissimus ) are two famous tea-like plants (non- Camellia sinensis tea) [ 13 , 14 ]. Vine tea is traditionally used both as medicine and food, and dihydromyricetin (DMY) is the abundant flavonoid and main bioactive component of vine tea [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Capacities and Polyphenol Contents of Kombucha Beverages Based on Vine Tea and Sweet Tea

et al. 2022

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Kombucha beverage is commonly prepared by black tea infusion fermentation without tea residues, and possesses various health benefits. In this paper, kombucha beverages of two non-Camellia sinensis teas, including vine tea (Ampelopsisgrossedentata) and sweet tea (Rubus suavissimus), were studied for the first time. The antioxidant activities and polyphenol contents of kombucha beverages were evaluated by ferric-reducing antioxidant power assay, Trolox equivalent antioxidant capacity assay, and Folin-Ciocalteu method, respectively. In addition, effects of tea residues on antioxidant capacities of kombucha beverages were evaluated. The results showed that kombucha beverages from vine tea and sweet tea possessed strong antioxidant activities (especially vine tea kombucha), and fermentation with tea residues could significantly increase antioxidant capacities (maximum increase of 38%) and total phenolic content (maximum increase of 55%) of two kombucha beverages compared with those without tea residues. Moreover, the sensory evaluations showed that the sensory evaluation scores of kombucha with tea residues could be improved compared with those without tea residues. Furthermore, the concentrations of several bioactive components in the kombucha beverages were detected by high-performance liquid chromatography. These kombucha beverages could be used for prevention of several diseases with related of oxidative stress.

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Section: Introductionmentioning

confidence: 99%

Antioxidant Capacities and Polyphenol Contents of Kombucha Beverages Based on Vine Tea and Sweet Tea

et al. 2022

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“…Flavonoids are of low-molecular-weight, comprising polyphenolic compounds, classified into six groups-isoflavonoids, flavanones, flavanols, flavonols, flavones, and anthocyanidins [11]. The primary source of these flavonoids is the regular human diet, including fruits, vegetables, grains, bark, roots, stems, flowers (Table 1 and Figure 1), plant-derived beverages, such as green tea, wine, and cocoa-based products [12][13][14][15][16][17][18][19][20]. Flavonoids have shown various activities, such as inhibiting cell proliferation and angiogenesis, cell cycle arrest, induction in apoptosis, and reversion in multidrug resistance [21,22].…”

Section: Introductionmentioning

confidence: 99%

Targeting PI3K/Akt/mTOR Pathway by Different Flavonoids: A Cancer Chemopreventive Approach

Zughaibi

Suhail

Tarique

et al. 2021

IJMS

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Cancer is, globally, one of the main causes of death. Even though various therapies are available, they are still painful because of their adverse side effects. Available treatments frequently fail due to unpromising responses, resistance to classical anticancer drugs, radiation therapy, chemotherapy, and low accessibility to tumor tissues. Developing novel strategies to minimize adverse side effects, improve chemotherapy sensitivity, and control cancer progression is needed. Many studies have suggested small dietary molecules as complementary treatments for cancer patients. Different components of herbal/edible plants, known as flavonoids, have recently garnered attention due to their broad biological properties (e.g., antioxidant, antiviral, antimicrobial, anti-inflammatory, anti-mutagenic, anticancer, hepatoprotective, and cardioprotective). These flavonoids have shown anticancer activity by affecting different signaling cascades. This article summarizes the key progress made in this area and discusses the role of flavonoids by specifically inhibiting the PI3K/Akt/mTOR pathway in various cancers.

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“…Moreover, extracts from vine tea have been proved to have significant anti-inflammatory properties in vitro and in vivo , and have been recommended as a potential therapeutic agent for inflammation-related diseases ( Chen et al, 2015 ). Importantly, the leaves and stems of vine tea are rich in a large number of natural active substance dihydromyricetin, which has become an important plant resource for the development and research of functional products ( Gao et al, 2009 ; Kou and Chen, 2012 ; Zhao et al, 2013 ; Zheng et al, 2014 ; Ye et al, 2015 ; Zhang et al, 2020 ; Carneiro et al, 2021 ). It is worth mentioning that as a natural active substance, dihydromyricetin from vine tea has been approved by the Food and Drug Administration (FDA) as a nutritional supplement and can be added in food industry.…”

Section: Introductionmentioning

confidence: 99%

Dihydromyricetin Reverses Thioacetamide-Induced Liver Fibrosis Through Inhibiting NF-κB-Mediated Inflammation and TGF-β1-Regulated of PI3K/Akt Signaling Pathway

et al. 2021

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As a natural active substance, dihydromyricetin (DHM) has been proven to have good hepatoprotective activity. However, the therapeutic effect of DHM on liver fibrosis, which has become a liver disease threatening the health of people around the world, has not been studied to date. The purpose of this study was to investigate the effect of DHM as a new nutritional supplement on thioacetamide (TAA)-induced liver fibrosis. The liver fibrosis model was established by intraperitoneal injection of TAA (200 mg/kg, every 3 days) for 8 weeks, and oral administration of DHM (20 mg/kg and 40 mg/kg, daily) after 4 weeks of TAA-induced liver fibrosis. The results showed that DHM treatment significantly inhibited the activities of alanine aminotransferase (ALT) (37.81 ± 7.62 U/L) and aspartate aminotransferase (AST) (55.18 ± 10.94 U/L) in serum of liver fibrosis mice, and increased the levels of superoxide dismutase (SOD) and glutathione (GSH) while reversed the level of malondialdehyde (MDA). In addition, histopathological examination illustrated that TAA induced the inflammatory infiltration, apoptosis and fibroatherosclerotic deposition in liver, which was further confirmed by western-blot and immunofluorescence staining. Moreover, DHM inhibited hepatocyte apoptosis by regulating the phosphorylation level of phosphatidylinositol 3-kinase (PI3K), protein kinase-B (AKT) and its downstream apoptotic protein family. Interestingly, immunofluorescence staining showed that DHM treatment significantly inhibited alpha smooth muscle actin (α-SMA), which was a marker of hepatic stellate cell activation, and regulated the expression of transforming growth factor (TGF-β1). Importantly, supplementation with DHM significantly inhibited the release of nuclear factor kappa-B (NF-κB) signaling pathway and pro-inflammatory factors in liver tissue induced by TAA, and improved liver fiber diseases, such as tumor necrosis factor alpha (TNF-α) and recombinant rat IL-1β (IL-1β). In conclusion, the evidence of this study revealed that DHM is a potential hepatoprotective and health factor, and which also provides the possibility for the treatment of liver fibrosis.

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Vine tea (Ampelopsis grossedentata): A review of chemical composition, functional properties, and potential food applications

Cited by 35 publications

References 51 publications

Antioxidant Capacities and Polyphenol Contents of Kombucha Beverages Based on Vine Tea and Sweet Tea

Antioxidant Capacities and Polyphenol Contents of Kombucha Beverages Based on Vine Tea and Sweet Tea

Targeting PI3K/Akt/mTOR Pathway by Different Flavonoids: A Cancer Chemopreventive Approach

Dihydromyricetin Reverses Thioacetamide-Induced Liver Fibrosis Through Inhibiting NF-κB-Mediated Inflammation and TGF-β1-Regulated of PI3K/Akt Signaling Pathway

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