Villous adenoma of the appendix with dysplasia

Karmarkar, Pragati; Joshi, Arun; Wilkinson, Anne; Mahore, Sadhana; Bothale, Kalpana

doi:10.4103/1319-3767.37807

Cited by 4 publications

(5 citation statements)

References 1 publication

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“…Serrated patterns may be seen in suspected areas. Epithelial cells can mimic the mucocele of the appendix [9][10][11].…”

Section: Discussionmentioning

confidence: 99%

Low-grade Appendiceal Mucinous Neoplasm (Appendiceal Villous Adenoma) with Cystic Fibrosis: A Case Report

Doğan

Avcı

et al. 2021

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Cystic fibrosis (CF) is an autosomal dominant disease characterized by the dysfunction of exocrine secretory glands resulting from a mutation in the transmembrane regulator protein (CFTR) gene. As life expectancy increases in patients with cystic fibrosis secondary to advances in treatment, advanced age malignancies secondary to cystic fibrosis emerge. Especially, the frequency of gastrointestinal system malignancies and colon cancers increases with aging. Appendiceal tumors are a rare entity and constitute less than 1% of gastrointestinal tumors. We presented a villous adenoma encountered in an 18-year-old male patient with CF accompanied by clinical and radiological findings. Our case is the first reported appendiceal tumor that emerged in patients with cystic fibrosis.

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“…Serrated patterns may be seen in suspected areas. Epithelial cells can mimic the mucocele of the appendix [9][10][11].…”

Section: Discussionmentioning

confidence: 99%

Low-grade Appendiceal Mucinous Neoplasm (Appendiceal Villous Adenoma) with Cystic Fibrosis: A Case Report

Doğan

Avcı

et al. 2021

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“…Once margin invasion is found, a right hemi-colectomy should be undertaken. Further therapy and evaluation of an association with neoplasia elsewhere must be considered [ 12 ]. Associations between synchronous or metachronous colon cancer (adenocarcinoma) and appendiceal adenomas have been noted.…”

Section: Discussionmentioning

confidence: 99%

“…Associations between synchronous or metachronous colon cancer (adenocarcinoma) and appendiceal adenomas have been noted. Thus, a colonoscopic examination may play an important role in patients with incidentally-discovered appendiceal tumours, and is particularly indicated in patients in the 6th-8th decades of life [ 12 , 13 ].…”

Section: Discussionmentioning

confidence: 99%

Perforated acute appendicitis resulting from appendiceal villous adenoma presenting with small bowel obstruction: a case report

et al. 2011

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BackgroundA villous adenoma is an extremely rare benign tumour in the appendix, in contrast to other benign appendiceal lesions. The clinical features are usually asymptomatic. Acute appendicitis is the most common complication with the lesion obstructing the orifice of the appendiceal lumen. Thus, a villous adenoma is usually found during surgical intervention for acute appendicitis. Mechanical obstruction induced by acute perforated appendicitis has been previously reported. Acute appendicitis caused by a villous adenoma presenting with acute intestinal obstruction has not been previously reported.Case presentationA 78-year-old woman presented to our Emergency Department with diffuse abdominal pain and tenderness. The abdominal plain film and computed tomography revealed an intestinal obstruction. After surgical intervention, the ruptured appendix was shown to be associated with intestinal obstruction. The post-operative pathologic diagnosis was an appendiceal villous adenoma.ConclusionsThis is the first report describing an appendiceal villous adenoma, which is an occasional cause of perforated acute appendicitis, presenting as a complete intestinal obstruction. We emphasize that in elderly patients without a surgical history, the occult cause of complete intestinal obstruction must be determined. If an appendiceal tumour is diagnosed, an intra-operative frozen section is suggested prior to selecting a suitable method of surgical intervention.

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“…Initially, the tumor grew and occluded the lumen of the appendix until mucus accumulated. Then the tumor cells are disseminated through the wall of the appendix into the peritoneal space [21]. The peritoneum was then seeded with mucusproducing cells, which continue to proliferate and produce mucus affecting the bowels.…”

Section: Ronnett Et Al (1995) Classified 109 Cases Of Pseudomyxoma Peritoneimentioning

confidence: 99%

“…Mortality due to the disease ranged from 2 to 31% with deaths occurring from 6 months to 12 years after diagnosis; with mean survival at 9 years. Reported complications of the procedure were anastomotic leaks, fistula formation, wound infection, small bowel perforation or obstructions and pancreatitis10 or this can be due to intra-abdominal mucus accumulation accompanied by fibrosis and complicated by small bowel obstruction [21,[24][25][26].…”

Section: Ronnett Et Al (1995) Classified 109 Cases Of Pseudomyxoma Peritoneimentioning

confidence: 99%

Pseudomyxoma Peritonei Revisited: A Case Report

2018

JGRM

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Bleeding after menopause raises suspicion of malignancy; more so, if combined with increased abdominal girth and constitutional symptoms. This is a case of a 74-year-old Gravida 10 Para 8 (8026) who presented with generalized abdominal pain, enlargement, bloatedness and vaginal bleeding. Ultrasound revealed a complex abdominopelvic mass, likely ovarian in origin. Tumor markers CA-125 and CA-199 were elevated. Endometrial curettage with frozen section revealed Leiomyosarcoma. It was followed by exploratory laparotomy revealing gelatinous material in the peritoneum with seeding of mucoid material into the omentum, ovary and appendix. Frozen section of the right ovary revealed Atypical Mucinous Proliferative Ovarian Tumor (APMOT). Final histopathology result of the endometrial curetting revealed adenomatoid tumor of the uterus. Immunohistochemical staining with desmin and caldesmon revealed negative results implicating the absence of leiomyosarcoma. Final histopathology results were consistent with Disseminated Peritoneal Adenomucinosis (DPAM). Immunohistochemical staining with CK20 was positive and CK7 was negative, consistent with metastases from a primary gastrointestinal tumor. Chemotherapy in the form of FOLFOX regimen was contemplated. However, the patient was lost to follow up.

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Villous adenoma of the appendix with dysplasia

Cited by 4 publications

References 1 publication

Low-grade Appendiceal Mucinous Neoplasm (Appendiceal Villous Adenoma) with Cystic Fibrosis: A Case Report

Low-grade Appendiceal Mucinous Neoplasm (Appendiceal Villous Adenoma) with Cystic Fibrosis: A Case Report

Perforated acute appendicitis resulting from appendiceal villous adenoma presenting with small bowel obstruction: a case report

Pseudomyxoma Peritonei Revisited: A Case Report

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