Vigorous exercise in patients with hypertrophic cardiomyopathy

Dejgaard, Lars A.; Håland, Trine Synnøve Fink; Lie, Øyvind; Ribe, Margareth; Bjune, Thea; Leren, Ida Skrinde; Berge, Knut Erik; Edvardsen, Thor; Haugaa, Kristina H.

doi:10.1016/j.ijcard.2017.07.015

Cited by 71 publications

(39 citation statements)

References 29 publications

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“…Until 2017, both United States and European guidelines for exercise and sports participation in patients with HCM had issued consistent recommendations against participation in all kinds of low-intensity competitive sports and even advised not to undertake vigorous activities on a recreational basis. However, recently, exercises such as long-term training, fitness, and sports activity were reported as beneficial in patients with HCM [ 10 , 11 ].…”

Section: Discussionmentioning

confidence: 99%

Painful and painless myocardial ischemia detected by elevated level of high-sensitive troponin in patients with hypertrophic cardiomyopathy

Gębka

Rajtar-Salwa

Dziewierz

et al. 2018

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Section: Discussionmentioning

confidence: 99%

Painful and painless myocardial ischemia detected by elevated level of high-sensitive troponin in patients with hypertrophic cardiomyopathy

Gębka

Rajtar-Salwa

Dziewierz

et al. 2018

pwki

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“…3 Conversely, a research conducted by Dejgaard (2017) stated that HCM individuals who has an active lifestyle have better cardiovascular function compared to inactive. 23 In line with Dejgaard, in an animal study conducted by Kim et al, mice induced with troponin I mutations without HCM phenotype, showed that exercise could reduce heart rate and increase contraction function. 15 In human studies, some researcher suggested that exercise was found to improve cardiac pathological structures in HCM patient by reducing myocytes disarray, decreasing clinical markers of ventricular hypertrophy and signal apoptosis.…”

Section: Guideline Recommendations For Exercise In Hypertrophic Cardimentioning

confidence: 79%

“…None reported adverse reaction such as fatal arrhythmia or sudden death related to exercise. 2,15,23,24 Saberi et al (2017) used 113 HCM samples which were randomized into two groups; training group and control group (usual activities). This research is referred to The Randomized Exploratory Study of Exercise in Hypertrophic Cardiomyopathy (RESET-HCM).…”

Section: Evidence-based Research For Exercise In Hypertrophic Cardiommentioning

confidence: 99%

Advantages of Exercise Training In Hypertrophic Cardiomyopathy: Considering risks and benefits

Tedjasukmana

2019

IJC

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Background. Hypertrophic cardiomyopathy (HCM) is one of the most common cardiac genetic disorders. The prevalence of this disease is 1 in 500 live births. It is stated to be the most frequent cause of sudden death in young adults. Therefore, some guidelines recommend to restrict physical activity and exercise. On the contrary, latest data show that active lifestyle and exercise in HCM patient provide significant benefits in cardiovascular function with no significant adverse reactions. Following to that, some experts might be reveal that its benefits might be outweigh risks. Summary. There is a paucity of studies that examine the effectiveness of exercise for HCM. American Heart Association (AHA) and (European Society of Cardiology) ESC established exercise recommendations for HCM individuals based on discussion and consensus of experts. We found three studies that investigate the efficacy of exercise in HCM individuals. Outcomes of our interest were differences in cardiovascular function, quality of life and safety issues. All studies found positive significant differences in main outcomes measure in which the HCM subjects on exercise had better or improved outcomes. None reported adverse reaction such as fatal arrhythmia or sudden death related to exercise. Brief Conclusion. Old belief regarding exercise restrictions on HCM need to be reconsidered, given that at present exercise have been shown to provide significant benefits for reducing cardiovascular risk factors. Nevertheless, exercise in patients with HCM must be specifically considered regarding the risk and benefit. Practicing active lifestyle and exercise on HCM individual is an exciting possibility that need further study. Keywords: hypertrophic cardiomyopathy, exercise training, risks and benefit, physical activity

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“…Hypertrophic cardiomyopathy genotype positive, phenotype negative (Genotype+ LVH-) and hypertrophic cardiomyopathy phenotype positive (HCM LVH+) patients were included. Inclusion commenced in 2001 and ended in 2015 [1] .…”

Section: Experimental Design Materials and Methodsmentioning

confidence: 99%

“…The data presented in this article are supplementary material to our study on vigorous exercise in hypertrophic cardiomyopathy patients. [1] .…”

Section: Datamentioning

confidence: 99%

Data on exercise and cardiac imaging in a patient cohort with hypertrophic cardiomyopathy

Dejgaard¹,

Håland²,

Lie³

et al. 2017

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Vigorous exercise in patients with hypertrophic cardiomyopathy

Cited by 71 publications

References 29 publications

Painful and painless myocardial ischemia detected by elevated level of high-sensitive troponin in patients with hypertrophic cardiomyopathy

Painful and painless myocardial ischemia detected by elevated level of high-sensitive troponin in patients with hypertrophic cardiomyopathy

Advantages of Exercise Training In Hypertrophic Cardiomyopathy: Considering risks and benefits

Data on exercise and cardiac imaging in a patient cohort with hypertrophic cardiomyopathy

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