Vigorous Exercise Can Cause Abnormal Pulmonary Function in Healthy Adolescents

Abstract

Rationale: Although exercise-induced bronchoconstriction is more common in adolescents with asthma, it also manifests in healthy individuals without asthma. The steady-state exercise protocol is widely used and recommended by the American Thoracic Society (ATS) as a method to diagnose exercise-induced bronchoconstriction. Airway narrowing in response to exercise is thought to be related to airway wall dehydration secondary to hyperventilation. More rigorous exercise protocols may have a role in detecting exercise-induced bronchoconstriction in those who otherwise have a normal response to steady-state exercise challenge.Objectives: The objective of this study was to determine the effect of two different exercise protocols-a constant work rate protocol and a progressive ramp protocol-on pulmonary function testing in healthy adolescents. We hypothesized that vigorous exercise protocols would lead to reductions in lung function in healthy adolescents.Methods: A total of 56 healthy adolescents (mean age, 15.2 6 3.3 [SD] years) were recruited to perform two exercise protocols: constant work rate exercise test to evaluate for exercise-induced bronchoconstriction (as defined by ATS) and standardized progressive ramp protocol. Pulmonary function abnormalities were defined as a decline from baseline in FEV 1 of greater than 10%.Measurements and Main Results: Ten participants (17.8%) had a significant drop in FEV 1 . Among those with abnormal lung function after exercise, three (30%) were after the ATS test only, five (50%) were after the ramp test only, and two (20%) were after both ATS and ramp tests.Conclusion: Healthy adolescents demonstrate subtle bronchoconstriction after exercise. This exercise-induced bronchoconstriction may be detected in healthy adolescents via constant work rate or the progressive ramp protocol. In a clinical setting, ramp testing warrants consideration in adolescents suspected of having exercise-induced bronchoconstriction and who have normal responses to steady-state exercise testing.

Regional lung function testing in children using electrical impedance tomography

“…There exist some studies on healthy children, adolescents and adults on bronchial responsiveness to exercise. [1][2][3][18][19][20] They show that some healthy subjects respond with a drop of FEV 1 (the prevalence varies widely); especially obese children are affected.…”

Knowledge and Perception of Self-Medication of Cough Medication in Pedicab Drivers in Surabaya

“…Interviews were conducted by asking the respondent whether there had been any orders to take passengers, to minimize the effect of strenuous activity that could affect the results of measuring lung function. 70 Complementary diseases in respondents were quite difficult to identify, because most respondents rarely went to a doctor if they had health problems. History of disease Various diseases such as bronchial asthma, allergies, sinusitis, heart disease, osteoporosis, and muscuskeletal diseases can affect lung function.…”