This chapter reviews some of the major overarching philosophical approaches to qualitative inquiry and includes some historical background for each approach. Taking a “big picture” view, the chapter discusses postpositivism, constructivism, critical theory, feminism, and queer theory and offers a brief history of these approaches; considers the ontological, epistemological, and axiological assumptions on which they rest; and details some of their distinguishing features. In the last section, attention is turned to the future, identifying three overarching, interrelated, and contested issues with which the field is being confronted and will be compelled to address as it moves forward: retaining the rich diversity that has defined the field, the articulation of recognizable standards for qualitative research, and the commensurability of differing approaches.