Vieillissement

Mialet‐Perez, Jeanne; Douin‐Echinard, Victorine; Cussac, Daniel; Bril, Antoine; Parini, Angelo

doi:10.1051/medsci/20153111015

Cited by 2 publications

(2 citation statements)

References 57 publications

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“…Au cours du vieillissement, l'altération de la structure et de la fonction cardiaque contribue à l'augmentation du risque de maladies cardiovasculaires et l'augmentation de la durée de vie rend de plus en plus pressante la nécessité de comprendre les mécanismes moléculaires du vieillissement cardiaque [44] …”

Section: Vieillissement Cardiaqueunclassified

Pathologies et vieillissement cardiaque

Perrin

Röder

2016

Med Sci (Paris)

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Section: Vieillissement Cardiaqueunclassified

Pathologies et vieillissement cardiaque

Perrin

Röder

2016

Med Sci (Paris)

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“…Ageing is a complex, multi-factorial psycho-biological process [1], which affects different organs and body systems, including heart, muscles, and lung [2]. In more detail, cardiac aging is characterized by decrease in left ventricular diastolic function [3] as well as by senescence of cardiomyocytes and cardiac stromal cells [4] and decreased cardiovagal baroreflex sensitivity [5], potentially resulting in heart failure and atrial fibrillation. Muscle size is reduced, and architecture altered in old age [6], with the number of motor units and muscle fibers being significantly decreased [7].…”

Section: Introductionmentioning

confidence: 99%

Dose-Response Relationship between Endurance Training Prescription Variables and Increases in Aerobic Performance of Healthy and Unhealthy Middle and Very Old Individuals Aged 70 Years and Older: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Cheour

Chéour

Bragazzi

et al. 2021

Life

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Background: The objectives of this systematic review and meta-analysis were to quantify the effectiveness of endurance training (ET) on aerobic performance (i.e., peak oxygen uptake (VO2peak)) in healthy and unhealthy middle and very old adults aged 70 years and older, and to provide dose–response relationships of training prescription variables (in terms of frequency, and volume). Methods: Several scholarly databases (i.e., PubMed/MEDLINE, SpringerLink, ScienceDirect Journals, and Taylor & Francis Online—Journals) were searched, identifying randomized controlled studies that investigated the effectiveness of ET on VO2peak in older adults. Standardized mean differences (SMD) were calculated. Results: In terms of changes differences between experimental and control group, ET produced significant large effects on VO2peak performance (SMD = 2.64 (95%CI 0.97–4.31)). The moderator analysis revealed that “health status” variable moderated ET effect onVO2peak performance. More specifically, ET produced larger SMD magnitudes on VO2peak performance in healthy compared with unhealthy individuals. With regard to the dose–response relationships, findings from the meta-regression showed that none of the included training prescription variables predicted ET effects on VO2peak performance. Conclusions: ET is an effective mean for improving aerobic performance in healthy older adults when compared with their unhealthy counterparts.

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Vieillissement

Cited by 2 publications

References 57 publications

Pathologies et vieillissement cardiaque

Pathologies et vieillissement cardiaque

Dose-Response Relationship between Endurance Training Prescription Variables and Increases in Aerobic Performance of Healthy and Unhealthy Middle and Very Old Individuals Aged 70 Years and Older: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

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