Videotaped Evaluation of Eyedrop Instillation in Glaucoma Patients with Visual Impairment or Moderate to Severe Visual Field Loss

Hennessy, Amy; Katz, Joanne; Covert, David; Protzko, C.; Robin, Alan L.

doi:10.1016/j.ophtha.2010.03.040

Cited by 93 publications

(114 citation statements)

References 23 publications

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“…Previous studies that video-recorded the performance of experienced glaucoma patients, evaluated their usual instillation technique. They have reported a success rate of 31% and 39% with the 2.5 ml and 5 ml bottle respectively [5][6][7][8][9][10][11][12][13][14]. Using the same triple criteria of success, the success rate of patient's usual technique of 41% in our study was consistent with previous studies.…”

Section: Discussionsupporting

confidence: 89%

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The effect of the Thai “Eye Drop Guide” on success rate of eye drop self-instillation by glaucoma patients

et al. 2014

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Background: Noncompliance can mislead clinicians regarding the efficacy of therapy and result in more aggressive, but inappropriate treatment. Improper techniques used for eye drop instillation frequently occurs in chronic glaucoma patients. The Thai Eye Drop Guide (EDG) device has been developed to ensure precise instillation. However, whether the EDG is more effective than the traditional technique when careful instructions for both techniques are given is still unknown. Objective: To compare success rates of eye drop self-instillation by chronic glaucoma patients using a traditional technique and the EDG when careful instructions for both are given. Methods: Fifty-nine chronic glaucoma patients were instructed to instill eye drops using the EDG or a traditional technique in a randomized sequence. A two week practice period was assigned before groups were crossed-over. The instillation performance was VDO recorded after each practice period. Three criteria of success: time taken to instill an eye drop into the eye; instillation of only one drop; and without the bottle tip touching lids, lashes, periocular tissues, or the other hand, were scored by three independent readers from video-records. The readers were blinded to the sequence to which the patients were randomized. Results: There were no significant differences in success rates between the EDG and traditional technique (61.0% and 66.1% respectively, p = 0.607) and the number of drops dispensed per application (median of 1 drop in both groups, p = 0.89). The time taken to instill eye drops with the EDG was significantly longer than using the traditional technique (median of 19 and 9 s respectively, p < 0.001). Older age (p = 0.049, OR 4.23) and more education (p = 0.025, OR 0.19) were found to be significantly associated with failure of the EDG. Conclusion: EDG is not more effective than a traditional technique in terms of improving dispensing accuracy and decreasing the drops dispensed per application even when careful instructions are given. The results suggest that, if good instructions are provided, experienced glaucoma patients can improve their eye drop instillation performance.

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Section: Discussionsupporting

confidence: 89%

“…Older age and more education were found to be a predictor of failure with the EDG. Older age and female sex was found to be associated with failure of eye drop instillation in previous studies [5,14,15]. By contrast, different results associated with educational level was observed in a multicenter study [3].…”

Section: Discussionmentioning

confidence: 83%

The effect of the Thai “Eye Drop Guide” on success rate of eye drop self-instillation by glaucoma patients

et al. 2014

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“…Good part of the analyzed studies did not mention the practice scenarios where they were performed [10][11][12][13][14]. The literature suggests that research should be communicated in a transparent manner so that readers can follow the methodology and draw clear conclusions.…”

Section: Discussionmentioning

confidence: 99%

“…Although papers evaluate instillation technique drops in patients with eye diseases, studies in almost its entirety, do not mention the literature used as reference to evaluate the technique [10][11][12][13][21][22][23][24][25][26]. According Vaidergorn et al, and Fraunfelder et al [27,28]instillation should be performed sitting or lying down, instilling eye drops only a single drop without contact from the bottle end with the ocular tissues.…”

Section: Discussionmentioning

confidence: 99%

Technical Evaluation of Eye Drops Instillation: A Systematic Review

Souza¹,

Rezende²,

Silva³

et al. 2017

JPP

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Abstract:Objective: Assess the profile of eye drops in patients with eye diseases. Methods: Studies available in the scientific literature were identified without any time limits using the databases Embase-Medline, Scielo, Scopus and Web of Knowledge. The selected studies were compared with the following inclusion criteria: (i) if the study evaluated the eye drop instillation, (ii) if the study involved participation of patients with eye diseases. Results: Twelve studies met the inclusion criteria. Of them, 83.33% evaluated the technique of eye drop instillation in patients with glaucoma, 8.33% in patients with eye diseases and 8.33% in patients with cataract after undergoing surgery to correct. 41.66% of studies have chosen to record a video of patients to analyze the technique of instilling eye drops and 41.66% did not describe the/esearch location. Regarding the type of study, 75% had the design as prospective cross-sectional, 8.33% prospective open label study, 8.33% intervention study and 8.33% study called masked trial. Although studies evaluate the technique of eye drop instillation, only 8.33% describe in the article the reference in the literature used to evaluate patients. 50% of articles acknowledged some sort of bias or limitation. Conclusion: The limitations inherent in these types of studies should guide future research.

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“…When medicationexperienced glaucoma patients were videotaped to evaluate their instillation technique, only 71% were able to get a drop onto the ocular surface, and only 39% were able to do this without touching the eye with the tip of the bottle. (Hennessy et al, 2010) Fully 24% of patients who denied touching the bottle to the ocular surface were shown to have contaminated the tip. Advanced patient age was the only significant predictor for less successful instillation.…”

Section: Parameters That Affect Instillationmentioning

confidence: 99%