Video head impulse test can detect brainstem dysfunction in multiple sclerosis

Video Head Impulse Test and central nervous system diseases: a integrative review

“…In the first selection phase, the titles and abstracts of the identified studies were evaluated, and only 21 of them addressed the study theme of this literature review. These publications were read in full and, after application of the eligibility criteria, 18 (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25) were selected to compose the final sample of this study. Figure 1 shows the detailed selection process of these publications.…”

“…From the information extracted from the 18 selected articles (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25) , a chart was created including data on disease, vestibular symptoms, and results of the vHIT and oculomotor tests (Chart 1).…”

“…All studies included in this literature review were published between 2014 and 2019. Regarding study design, there were seven case reports (8,9,14,18,22,23,25) , four case series (13,19,21,24) , six case controls (10)(11)(12)15,16,20) , and one cross-sectional study (17) .…”

“…The sample size ranged from 1 to 63, with age or mean age of participants between 25 and 77 years. The strength of scientific evidence was classified as level 5 for 11 articles (8,9,13,14,18,19,(21)(22)(23)(24)(25) and level 4 for seven articles (10)(11)(12)(15)(16)(17)20) . This was since most studies were case reports, followed by case controls, which are designs with a low grade of recommendation because they are more likely to be biased.…”

“…As for Chart 1, the following CNS disorders were studied: cerebellar stroke (8,12,17,23) , multiple sclerosis (MS) (9,10,20) , cerebellar ataxia with neuropathy, and vestibular areflexia syndrome (CANVAS) (19,22,24) , superficial siderosis of the CNS (14,21) , Wernicke encephalopathy (18) , left inferior cerebellar peduncle glioma (25) , progressive supranuclear palsy (PSP) (11) , mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke (MELAS syndrome) (13) , Parkinson's disease (PD) (16) , spinocerebellar ataxia types 1 (SA1), 2 (SA2) and 3 (SA3) and Friedreich's ataxia (FA) (15) .…”