Video capsule endoscopy in pediatric patients with Crohn’s disease: a single-center experience of 180 procedures

Németh, Artúr; Agardh, Daniel; Johansson, Gabriele Wurm; Thorlacius, Henrik; Tóth, Ervin

doi:10.1177/1756284818758929

Cited by 5 publications

(3 citation statements)

References 35 publications

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“…Case reports have demonstrated that VCE is safe to use in children as young as 8 months or weighing as little as 7.9 kg. [ 11 , 12 ] The usefulness of VCE in children has been established for several small-bowel pathologies, such as Crohn's disease, [ 13 ] obscure gastrointestinal bleeding, [ 14 ] hereditary polyposis, [ 15 ] abdominal pain, and protein-losing enteropathy. [ 4 , 16 ] Furthermore, VCE is well suited for longitudinal monitoring of Crohn's disease activity in the small bowel.…”

Section: Discussionmentioning

confidence: 99%

Clinical features of capsule endoscopy in 825 children

Huang

Wang

et al. 2020

Medicine

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Video capsule endoscopy (VCE) can detect mucosal lesions in the intestine, especially in the small bowel. Our study aims to evaluate the applications of VCE for pediatric gastrointestinal diseases. In this retrospective study, we included all patients who underwent VCE between December 2012 and December 2018. Clinical information and VCE data were analyzed. Among 828 patients, the completion rate was 99.6% (n = 825), with an average age of 10.2 ± 3.3 years old. A total of 459 VCE procedures showed abnormalities, and the overall diagnostic yield was 55.6%. The most common indications for VCE were abdominal pain among 505 (61.2%) patients and hematochezia (10.1%) among 83. Among the positive results of VCE, small bowel ulcers accounted for the highest percentage (57.7%), of which 164 cases were diagnosed as inflammatory bowel disease. For obscure gastrointestinal bleeding, 12 cases were diagnosed as Meckel's diverticulum. In terms of the small bowel transit time of VCE, compared with the negative group [288 (216.5, 390.3) min] and the enteritis group [277 (192.5, 374.8) min], a longer transit time was needed in the small bowel ulcer group [332.5 (240, 451.5) min, P < .01]. There were no correlations of positive VCE findings with anemia, the white blood cell count, the C-reactive protein level or the small bowel transit time according to Spearman rank analysis. VCE is relatively well tolerated and safe in children and has great value for the diagnosis and treatment of abdominal pain, especially inflammatory bowel disease and obscure gastrointestinal bleeding.

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Section: Discussionmentioning

confidence: 99%

Clinical features of capsule endoscopy in 825 children

Huang

Wang

et al. 2020

Medicine

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“…Video capsule endoscopy (VCE) can detect mucosal lesions in the small bowel and is useful in evaluating small bowel involvement in suspected CD 53–55 . Its use has also resulted in a change in diagnosis from previously diagnosed UC to CD 53 or reclassification of the phenotype in confirmed CD cases 60 .…”

Section: Disease Monitoringmentioning

confidence: 99%

“…can detect mucosal lesions in the small bowel and is useful in evaluating small bowel involvement in suspected CD. [53][54][55] Its use has also resulted in a change in diagnosis from previously diagnosed UC to CD 53 or reclassification of the phenotype in confirmed CD cases. 60 However, the role of VCE in monitoring disease activity in small bowel CD has not been fully established.…”

Section: Video Capsule Endoscopy Video Capsule Endoscopy (Vce)mentioning

confidence: 99%

Management and monitoring of pediatric inflammatory bowel disease in the Asia‐Pacific region: A position paper by the Asian Pan‐Pacific Society for Pediatric Gastroenterology, Hepatology, and Nutrition (APPSPGHAN) PIBD Working Group: Surgical management, disease monitoring, and special considerations

Lee

Arai

Alex

et al. 2023

J of Gastro and Hepatol

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Disease phenotype of pediatric inflammatory bowel disease (PIBD) in children from the Asia-Pacific region differs from that of children from the West. Many parts of Asia are endemic for tuberculosis, making diagnosis and management of pediatric Crohn's disease a challenge. Current available guidelines, mainly from Europe and North America, may not be completely applicable to clinicians caring for children with PIBD in Asia due to differences in disease characteristics and regional resource constraints. This position paper is an initiative from the Asian Pan-Pacific Society for Pediatric Gastroenterology, Hepatology and Nutrition (APPSPGHAN) that aims to provide an up-to-date, evidence-based approach to PIBD in the Asia-Pacific region. A group of pediatric gastroenterologists with a special interest in PIBD performed an extensive literature search covering epidemiology, disease characteristics and natural history, management, and monitoring. Attention was paid to publications from the region with special consideration to a resource-limited setting. This current position paper deals with surgical management, disease monitoring, immunization, bone health, and nutritional issues of PIBD in Asia. A special section on differentiating pediatric Crohn's disease from tuberculosis in children is included. This position paper provides a useful guide to clinicians in the surgical management, disease monitoring, and various health issues in children with IBD in Asia-Pacific region.

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