Video-assisted thoracoscopic thymectomy for thymoma: a single-center experience

Abstract

Background Thymoma is a primary tumor derived from the epithelial cells of the thymus, which is commonly seen in the mediastinum. Surgical thymectomy is the radical treatment for thymoma. The recent introduction of video-assisted thoracoscopic surgery has improved the quality of thymectomy surgery. The clinical characteristics of thymoma and the outcomes of video-assisted thoracoscopic thymectomy in Vietnamese patients are still lacking. The objectives of this study were to investigate the clinical and laboratory characteristics of thymoma and to evaluate the early results of video-assisted thoracoscopic thymectomy for thymoma in Vietnamese patients. Methods All 53 thymoma patients with or without myasthenia gravis who underwent video-assisted thoracoscopic thymectomy in Military Hospital 103, Vietnam, from October 2013 to July 2017 were included. Results The mean age was 46.5 7.1 years, and the female/male ratio was 1.2:1. Myasthenia gravis, mostly stage IIA, was present in 84.9% of patients. There was no hospital mortality or major postoperative complication. The mean operative time was 65 min, intensive care unit stay was 22 ± 5 h, and postoperative hospital stay was 7.5 ± 1.7 days. Conclusion Thoracoscopic thymectomy for thymoma in Vietnamese patients achieved improved cosmesis and was safe for both non-myasthenia gravis and myasthenia gravis patients.

Comparing the safety and efficacy of thoracoscopic surgery and thoracotomy for thymoma: a systematic review and meta-analysis

“…Therefore, a high risk of bias exists. Meanwhile, the included cohort studies were limited by study design, and the reliability of the meta-analysis is poor (37). Secondly, the tumor status (pathological grade, clinical stage) of each study, which may cause bias to the results.…”

Advances in Understanding and Managing Myasthenia Gravis: Current Trends and Future Directions

“…The objectives of this study were to examine the clinical and biochemical features of thymoma and evaluate the initial results of video-assisted thoracoscopic thymectomy for thymoma in Vietnamese patients. The study comprised all 53 patients with thymoma, regardless of whether they had MG, who had video-assisted thoracoscopic thymectomy at Military Hospital 103 in Vietnam between October 2013 and July 2017 [ 38 ]. Using information from two recently concluded treatment studies for GMG, the results of the MMT (Manual Muscle Test), MG-ADL (myasthenia gravis-activities of daily living), and quantitative myasthenia gravis (QMG) scales.…”

Neuromuscular diseases and anesthesia

“…Pokazan je benefit od ove operacije i kod obolelih od mijastenije, a koji nemaju timom. Pokazano je značajno smanjenje potrebne doze imunosupresivne terapije, a egzacerbacije bolesti i potrebne hospitalizacije su značajno ređe 4,5 . Najčešće se za lečenje ove bolesti koriste 8 : -Inhibitori acetilholinesteraze, kao prva terapijska opcija.…”