Video‐assisted thoracoscopic lobectomy with a single utility port is feasible in the treatment of elderly patients with peripheral lung cancer

Abstract

Background: Video-assisted thoracoscopic (VATS) lobectomy with a single utility port has emerged as a new technology in recent years. The aim of this study is to review the technology in the treatment of elderly patients with peripheral lung cancer. Methods: We retrospectively analyzed the clinical data of 21 elderly patients with peripheral lung cancer who underwent single utility port VATS lobectomy from February 2011 to February 2013 in the First Affiliated Hospital of Soochow University (VATS group). The clinical outcomes and postoperative complications were then compared to data from 32 elderly patients who underwent lobectomy by thoracotomy (TL group). Results: No mortality occurred during the postoperative period in either group. There was no statistical difference in surgery duration, the quantity of lymph node dissection or intraoperative blood loss between the VATS and TL groups. However, significant differences existed in the postoperative hospital stay (6.19 ± 1.69 days vs. 8.22 ± 2.55 days), time to first activity out of bed (20.57 ± 7.72 hours vs. 26.81 ± 9.27 hours), chest drainage duration (4.24 ± 1.04 days vs. 5.22 ± 1.29 days), and total postoperative drainage volume (642.86 ± 158.18 mL vs. 787.81 ± 211.55 mL) between the VATS and TL groups (P < 0.05). The percentage of patients with no complications in the VATS group (85.71%) is significantly higher when compared with the TL group (56.25%, P < 0.05). Conclusion: VATS lobectomy with a single utility port is a safe and feasible surgical procedure for selected elderly patients with peripheral lung cancer.

Optimal Approach to Lobectomy for Non-Small Cell Lung Cancer: Systemic Review and Meta-Analysis

“…Only one study including 53 patients showed that uVATS patients had a significantly reduced length of hospital stay compared to open lobectomy. 88 The mean hospital stay for uVATS patients was 2.03 days less than open lobectomy patients (95% CI −3.17 to – 0.89; P = 0.0005).…”

“…154 One study compared uVATS to open lobectomy. 88 Four studies compared mVATS to rVATS and open lobectomy. 37,116,132,164 Two studies compared minimally invasive surgery (mVATS and rVATS combined) to open lobectomy.…”

Uniportal video-assisted thoracoscopy surgery in lung cancer: largest experience

“…A number of publications have focused on this technique, but they are mainly case reports and small series. 6–14 Ismail and colleagues, 8 Duan and colleagues, 10 and Erşen and colleagues 11 discussed their experience of UVATS for lobar and sublobar resections for lung cancer and found it to be noninferior to conventional multiport VATS in terms of surgical outcomes, and better in terms of postoperative recovery and hospital stay. However, a multicentric randomized trial concluded that sublobar resection is not a standard of care for the management of lung cancer, and it was associated with increased locoregional recurrence rates without any significant improvement in perioperative morbidity and mortality, recommending that sublobar resection be performed only in patients with significantly reduced pulmonary reserve.…”

MicroRNA-203 inhibits cellular proliferation and invasion by targeting Bmi1 in non-small cell lung cancer

“…Lung cancer is currently the most common type of cancer worldwide in terms of incidence and mortality, and non-small cell lung cancer (NSCLC) accounts for 85% of all lung cancer cases (1). There remains a lack of effective biomarkers or indicators for diagnosis, which often leads to delayed diagnosis and thus the majority of patients with NSCLC present with an advanced stage.…”