Video‐assisted anal fistula treatment for complex anal fistula: a long‐term follow‐up study, Giarratano et al

Clark, Shanetia P.

doi:10.1111/codi.15222

Cited by 2 publications

(2 citation statements)

References 4 publications

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“…This is so because unlike fistulotomy, which can be safely done in low fistulae with a success rate of 90%-98%, 18 most sphincter-saving procedures have a success rate of 30%-68%. 1,15,[19][20][21][22][23][24][25][26][27] Therefore, overestimation of sphincter involvement can lead to selection of a surgical procedure with a lower success rate.…”

Section: Assessing the Extent Of Sphincter Involvement: Mrimentioning

confidence: 99%

Management of Complex Cryptoglandular Anal Fistula: Challenges and Solutions

Garg¹,

Sodhi²,

Garg³

2020

CEG

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Anal fistulae can be a very difficult disease to manage. The management of complex fistulae is even more challenging. The risk to the fecal continence mechanism due to damage to the anal sphincters and refractoriness to the treatment (high recurrence rate) pose the two biggest challenges in the management of this disease. Apart from these, there are several other challenges in the treatment of complex fistulae. The intriguing and uphill task is that satisfactory solutions to most of these challenges are still not known, and there is hardly any consensus on whatever treatment solutions are available. To summarize, there is no gold-standard treatment available for treating complex anal fistulae, and the search for a satisfactory treatment option is still on. In this review, the endeavor has been to discuss and highlight recent path-breaking updates in the management of complex anal fistulae.

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Section: Assessing the Extent Of Sphincter Involvement: Mrimentioning

confidence: 99%

Management of Complex Cryptoglandular Anal Fistula: Challenges and Solutions

Garg¹,

Sodhi²,

Garg³

2020

CEG

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“…At present, the surgical approaches for patients with anal fistula include fistulotomy, seton, video-assisted anal fistula treatment (VAAFT), autologous adipose-derived stem cells (especially for Crohn's fistula-in-ano), mucosal advancement flap, ligation of intersphincteric fistula tract (LIFT), fibrin sealant, biologic fistula plugs, synthetic fistula plug and fistula tract laser closure [12][13][14][15]. They can cure some types of anal fistula on the premise of maximum protection of anal function, but there is a lack of high-quality evidence supporting an optimal procedure for certain types of anal fistula.…”

Section: Introductionmentioning

confidence: 99%

Surgical treatment for cryptoglandular and Crohn’s perianal fistulas: Protocol of an umbrella review

Mei

Feng

et al. 2021

PLoS ONE

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Introduction A high prevalence of cryptoglandular and Crohn’s perianal fistulas has been reported worldwide, and several surgical options are available for the management of anal fistula, with varying clinical efficacy. However, currently, the available evidence for the effectiveness of these surgical approaches are lacking and of concern in terms of the credibility and strength. The purpose of this study is to evaluate the credibility of the published systematic reviews and meta-analyses that assess the efficacy and safety of the surgical options for cryptoglandular and Crohn’s perianal fistulas through an umbrella review. Methods and analysis A systematic search in PubMed, Embase and Cochrane library will be performed from inception to December 2020 without any language restriction. We will include systematic reviews and meta-analyses that investigate the efficacy and safety of surgical approaches in the management of cryptoglandular and Crohn’s perianal fistulas. Two reviewers will independently screen search results through reading the titles or abstracts. Relevant information will be extracted from each eligible systematic review or meta-analysis. Based on random effects model summary estimates along with their p values, 95% prediction intervals, between-study heterogeneity, small-study effects and excess significance, we will classify the evidence from convincing (class I) to weak (class IV). Findings will be summarized using quantitative synthesis combined with a narrative approach. Cryptoglandular and Crohn’s perianal fistulas will be summarized separately. Two authors will independently perform the literature search, data extraction, and quality assessment of each included systematic review and meta-analysis. Any unresolved conflicts or doubts will be resolved by discussion or by consulting a senior author. The risk of bias of the systematic reviews will be assessed using a 16-item Assessment of Multiple Systematic Reviews 2 (AMSTAR2) checklist. The strength of evidence for the included systematic reviews will be classified as "high", "moderate", "low", or "critically low" quality. Ethics and dissemination Ethics approval is not required as we will collect data from the published systematic reviews and meta-analyses without using individual patient data. The results of this umbrella review will be published in a peer-reviewed journal and will be presented at an anorectal disease conference. PROSPERO registration number CRD42020200754.

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Video‐assisted anal fistula treatment for complex anal fistula: a long‐term follow‐up study, Giarratano et al

Cited by 2 publications

References 4 publications

<p>Management of Complex Cryptoglandular Anal Fistula: Challenges and Solutions</p>

<p>Management of Complex Cryptoglandular Anal Fistula: Challenges and Solutions</p>

Surgical treatment for cryptoglandular and Crohn’s perianal fistulas: Protocol of an umbrella review

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