Vichy Thermal Spring Water (<scp>VTSW</scp>), a cosmetic ingredient of potential interest in the frame of skin ageing exposome: an <i>in vitro</i> study

Tacheau, Charlotte; Weisgerber, F.; Fagot, Dominique; Bastien, Philippe; Verdier, Marie Paule; Liboutet, M.; Sore, Gabrielle; Bernard, Bruno

doi:10.1111/ics.12470

Cited by 19 publications

(26 citation statements)

References 70 publications

(101 reference statements)

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“…12 Moreover, internal data confirmed that M89 is beneficial in reinforcing and restoring the skin barrier integrity and that it protects against adhesion of pollution microparticles. 12 Moreover, internal data confirmed that M89 is beneficial in reinforcing and restoring the skin barrier integrity and that it protects against adhesion of pollution microparticles.…”

Section: Introductionmentioning

confidence: 82%

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Vichy mineralizing water with hyaluronic acid is effective and well tolerated as an adjunct to the management of various dermatoses and after esthetic procedures

Tan

Spada²,

Orlandi

et al. 2019

J of Cosmetic Dermatology

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Introduction: M89, containing 89% of Vichy mineralizing water and hyaluronic acid, has been developed to reinforce the skin barrier and to improve skin quality. Aim:To assess efficacy and tolerability of M89. Method:Observational survey of subjects with facial dermatoses or after esthetic procedures. M89 served as adjunct to conventional therapy. Clinician assessments of erythema, desquamation, irritation and patient-reported dryness, burning, itching, and stinging/tingling were conducted at baseline and 4 weeks. At 1 week and 4 weeks, patient assessed tolerance and satisfaction with M89.Results: A total of 1630 subjects participated; 92.5% were females. Mean age was 41.1 ± 11.3 years. Dermatological indications accounted for 32.5%, procedures for 67.5%. At 4 weeks, in subjects with dermatoses, erythema had resolved or improved in 68.0%, desquamation in 83.4%, and irritation in 93.3%. Dryness, burning, itching, and | 683 TAN eT Al.

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Section: Introductionmentioning

confidence: 82%

“…In vitro and in vivo studies on M89 and its ingredients have confirmed its potential to support skin barrier function. 12 Moreover, internal data confirmed that M89 is beneficial in reinforcing and restoring the skin barrier integrity and that it protects against adhesion of pollution microparticles.…”

Section: Introductionmentioning

confidence: 82%

Vichy mineralizing water with hyaluronic acid is effective and well tolerated as an adjunct to the management of various dermatoses and after esthetic procedures

Tan

Spada²,

Orlandi

et al. 2019

J of Cosmetic Dermatology

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“…Results from this split-face study confirm the clinical benefit of M89 in subjects with rosacea with erythema and sensitive skin to reinforce the natural defences of the skin in restoring the natural skin barrier, stimulating antioxidant activity and reducing inflammation, commonly observed in subjects with rosacea. [18][19][20][21][22][23][24][25]31 Daily use of M89 led to a significant improvement of erythema, skin tightness and skin dryness sensations after 15 and 30 days of treatment compared to usual skin care products. Similarly, statistically significant decreases in the mean basal scores of skin sensitivity, detected by means of a sting-test, were recorded after 15 and 30 days of treatment with M89, although no statistically significant variation was recorded in the same parameter after the treatment with the usual skin care product.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…These minerals reinforce the natural defences of the skin in restoring the natural skin barrier, stimulating antioxidant activity and reducing inflammation, commonly observed in subjects with rosacea. [18][19][20][21][22][23][24][25] In an unpublished analysis of a global investigation concerning a subgroup of subjects with mild rosacea, M89 applied daily on the face improved clinical signs of rosacea and, according to subjects, improved their symptoms as well as skin hydration, indicating that M89 may strengthen the natural skin barrier and help to protect the skin from environmental and external aggressions. 26 The aim of our split-face study was to assess the clinical benefit of M89 compared to standard skin care in subjects with rosacea with erythema and sensitive skin after 30 days of daily use.…”

Section: Introductionmentioning

confidence: 99%

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<p>A Split-Face Study Assessing the Clinical Benefit, Tolerability and Subject Satisfaction of a Dermocosmetic in Subjects with Rosacea Associated with Erythema and Sensitive Skin</p>

Berardesca¹,

Bonfigli²,

Cribier³

et al. 2020

CCID

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This study assessed the efficacy and tolerability of M89 in patients with rosacea associated with erythema and sensitive skin. Methods: Intra-individual study in a split-face design comparing after 30 days M89 twice daily and usual skin care in 20 adult subjects with rosacea and sensitive skin. M89 contains 89% Vichy volcanic mineralizing water (VVMW) and 0.4% hyaluronic acid. It is hypoallergenic and contains no perfume and this convenes in rosacea. Contained minerals reinforce the natural defences of the skin in restoring the natural skin barrier, stimulating antioxidant activity and reducing inflammation, commonly observed in subjects with rosacea. Clinical evaluations included assessment of erythema, desquamation, papules and pustules, skin tightness, dryness, burning sensation, itching, stinging and stinging test as well as local tolerability. Instrumental evaluations included skin hydration and TEWL. Subject satisfaction was assessed at Days 15 and 30. Demodex density was assessed at Day 30. Results: A significant superiority of M89 over the standard skin care was observed for erythema, skin tightness and dryness (all P≤0.05) as early as Day 15, the skin stinging test was significantly in favour of M89 (P<0.05 at Day 15 and P<0.01 at Day 30) and for skin hydration (P<0.0001) at Day 15 and 30 with no difference in mean Demodex density between M89 and usual skin care after 30 days. Tolerance was excellent and subject satisfaction very high. Conclusion: Study results concerning M89 are encouraging for its use either alone or as an adjuvant daily skin care to topical medication in patients with persistent centrofacial erythema of rosacea with no more than 3 papules and pustules.

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Skin Exposome

Sore

Lynch

2022

Cosmetic Dermatology

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Vichy Thermal Spring Water (VTSW), a cosmetic ingredient of potential interest in the frame of skin ageing exposome: an in vitro study

Abstract: This work suggests that VTSW could be considered as an ingredient of potential interest to address some of the deleterious effects of skin ageing exposome.

Cited by 19 publications

References 70 publications

Vichy mineralizing water with hyaluronic acid is effective and well tolerated as an adjunct to the management of various dermatoses and after esthetic procedures

Vichy mineralizing water with hyaluronic acid is effective and well tolerated as an adjunct to the management of various dermatoses and after esthetic procedures

<p>A Split-Face Study Assessing the Clinical Benefit, Tolerability and Subject Satisfaction of a Dermocosmetic in Subjects with Rosacea Associated with Erythema and Sensitive Skin</p>

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