This review aims to shed light on the symptoms in obsessive-compulsive disorder, with a focus on contamination fears. In addition, we will briefly review the current therapies for OCD and detail what their limitations are. A key focus will be to discuss how smartphone solutions may provide approaches to novel treatments, especially when considering global mental health and the challenges imposed by rural environments and limited resources; as well as restrictions imposed by worldwide pandemics such as COVID-19. In brief, research questions this review will seek to address include: (1) what are the symptoms in contamination-related OCD; (2) how effective are current OCD therapies and what are their limitations; and (3) how can novel technologies help mitigate challenges imposed by global mental health and pandemics/COVID-19.