Viability of Spermatozoa in the Human Ejaculate After Vasectomy

Bedford, J. M.; Zelikovsky, G

doi:10.1016/s0015-0282(16)44305-0

Cited by 21 publications

(8 citation statements)

References 13 publications

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“…The fertilizing ability of the spermatozoa in the post-vasectomy samples was analysed with the zona-free hamster egg penetration test, and the mean + s.e.m. penetration rate of 20-6 ± 60 observed was significantly lower (P < 0-001) than the pre-vasectomy score of 49-7 ± 6-4% ( (Bedford & Zelikovsky, 1979) and in 100% of samples by Day 15 (Jouannet & David, 1978).…”

Section: Resultsmentioning

confidence: 68%

The functional competence of human spermatozoa recovered after vasectomy

Richardson¹,

Aitken²,

Loudon³

1984

Reproduction

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Summary. Progresssively motile spermatozoa were present in 42/47 (89%) of post \ x=r eq-\ vasectomy specimens, and in 16 of 24 samples (66%) demonstrable fertilizing potential could be detected in the zona-free hamster egg assay. The mean \m=+-\ s.e.m. post \ x=req-\ vasectomy penetration rate of 20\m=.\6 \m=+-\6\m=.\0%was, however, significantly lower (P < 0\m=.\001) than the pre-vasectomy value of 49\m=.\7 \m=+-\6\m=.\4%. After vasectomy the concentration of motile spermatozoa in the ejaculates declined in a manner that was significantly correlated with the post-operative time interval. The spermatozoa also lost their potential for fertilization, although functionally competent spermatozoa were still being recovered from ejaculates produced 8 days after vasectomy.These results emphasize the ability of human spermatozoa to retain some residual fertilizing potential when stored at core body temperature in sites distal to the epididymis, and suggest a role for functional tests in the management of the vasectomized male.

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Section: Resultsmentioning

confidence: 68%

The functional competence of human spermatozoa recovered after vasectomy

Richardson¹,

Aitken²,

Loudon³

1984

Reproduction

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“…Motile sperm disappear within a few weeks after vasectomy (318)(319)(320)(321). The time to azoospermia varies widely in different studies; however, by 12 weeks after the vasectomy, 80% of men have azoospermia, and almost all others have rare nonmotile sperm (defined as ≤100,000 nonmotile sperm per milliliter) (317).…”

Section: Other Postprocedures Recommendationsmentioning

confidence: 99%

U.S. Selected Practice Recommendations for Contraceptive Use, 2016

Curtis

Jatlaoui²,

Tepper³

et al. 2016

MMWR Recomm. Rep.

339

351

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The 2016 U.S. Selected Practice Recommendations for Contraceptive Use (U.S. SPR) addresses a select group of common, yet sometimes controversial or complex, issues regarding initiation and use of specific contraceptive methods. These recommendations for health care providers were updated by CDC after review of the scientific evidence and consultation with national experts who met in Atlanta, Georgia, during August 26-28, 2015. The information in this report updates the 2013 U.S. SPR (CDC. U.S. selected practice recommendations for contraceptive use, 2013. MMWR 2013;62[No. RR-5]). Major updates include 1) revised recommendations for starting regular contraception after the use of emergency contraceptive pills and 2) new recommendations for the use of medications to ease insertion of intrauterine devices. The recommendations in this report are intended to serve as a source of clinical guidance for health care providers and provide evidence-based guidance to reduce medical barriers to contraception access and use. Health care providers should always consider the individual clinical circumstances of each person seeking family planning services. This report is not intended to be a substitute for professional medical advice for individual patients. Persons should seek advice from their health care providers when considering family planning options.

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“…The attempt to shorten the postoperative time period estimated for the attainment of andrologia 18 (1986) The azoospermia in the ampulla area of the vas deferens detected in animal experiments after only four weeks gives rise to further considerations: the number of ejaculations taking place postoperatively could not be taken into account for the animal experiments. If, however, the frequently described dependence of azoospermia on the number of ejaculations (Bedford and Zelikovsky -1979;Craft -1973;Lehtonen -1975;Marshall and Lyon -1972;Spencer and Charlesworth -1976) is of any importance in humans in connection with the application of polyvidone-iodine*, it is quite conceivable that sterility can be attained here in even shorter time periods. It should be the object of further investigations to clarify this point.…”

Section: Discussionmentioning

confidence: 99%

“…Spermatic duct occlusion corresponds to the ovulation inhibitors in ints contraceptive reliability; moreover, the intervention is described as being technically simple and can be carried out on an outpatient basis (Bandhauer and Obermayer -1972;Schmidt -1971; Various opinions exist regarding the time period estimated for the attainment of sterility: while some authors consider only a few weeks to be necessary (Esho and Cass -1973;Frick -1983), others refer in this connection to intervals of several month postoperatively (Klosterhalfen -1976;Konietzko und Reinecke -1973;Temple and Jameson -1970); greater importance for the attainment of sterility is frequently attached to the number of ejaculations that have taken place after the intervention than to the time that has passed (Bedford and Zelikovsky -1979;Errey -1973;Marshall and Lyon -1972;Spencer and Charlesworth -1976). Two ejaculates with the picture of azoospermia is regarded by most operators as sufficient proof for the infertility of the man after the performance of spermatic duct occlusion (Craft and McQueen -1972;Marshall -1979;Schmidt -1966).…”

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confidence: 99%

Examinations of Polyvidone-lodine* as an Irrigation Solution for Spermatic Duct Occlusions

2009

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In vitro experiments with human sperm as well as animal experiments were carried out to test the applicability of polyvidone-iodine as an imgation solution for spermatic duct occlusions.The substance polyvidone-iodine was initially chosen on the basis of spenniograms because of its ability to immobilize spermatozoa, and then its spermicidal effect was clearly proven by means of eosin vital staining. The aim of the animal experiments was to examine the substance for possible histotoxic side effects and to ascertain the retention of residual sperm in the ampulla area of the vas deferens.ely spermicidal with no long-term histotoxic side effects; in addition, it acts as a disinfectant and is easily obtainable as well as inexpensive. Postoperative azoospermia is attained in animal experiments after four weeks at the most.Polyvidone-iodine fulfills all the required criteria as an irrigation solution: it is definit- Untersuchungen des PolyvinylpyrrolidonJod* als Spiillosung bei VasokklusionenZusammenfassung: Mit In-vitro-Versuchen an menschlichem Sperma und in Tierexperimenten wurde die Venvendbarkeit des Polyvinylpyrrolidon-Jod als Spiillosung bei Vasokklusionen getestet.Fiir die zunachst anhand von Spermiogrammen wegen ihrer Fiihigkeit, Spermien zu immobilisieren, ausgewiihlte Substanz Polyvinylpyrrolidon-Jod wurde dann mittels der Eosin-Vitalfiirbung eine eindeutige Spermizidie nachgewiesen. Die Tierexperimente dienten einerseits zur Untersuchung der Substanz auf mogliche histotoxische Nebenwirkungen, zum anderen zielten sie auf die Feststellung der Venveildauer von Restspermien im Ampullenbereich des Vas deferens ab.Das Polyvinylpyrrolidon-Jod erfiiillt als Spiillosung alle geforderten Kriterien: es ist sicher spermizid bei Fehlen langfristiger histotoxischer Nebenwirkungen, wirkt zudem desinhierend und ist leicht verfugbar wie auch preisgiinstig. Die postoperative Azoospermie ist im Tierexperiment nach Engstens vier Wochen gegeben. IntroductionThe increasingly more critical attitude towards hormonal contraceptives (Schirren and Scholz-Jordan -1976) has in recent contributed towards an intensification of the search for applicable contraceptive methods for men. Spermatic duct occlusion presently repre-

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Viability of Spermatozoa in the Human Ejaculate After Vasectomy

Cited by 21 publications

References 13 publications

The functional competence of human spermatozoa recovered after vasectomy

The functional competence of human spermatozoa recovered after vasectomy

U.S. Selected Practice Recommendations for Contraceptive Use, 2016

Examinations of Polyvidone-lodine* as an Irrigation Solution for Spermatic Duct Occlusions

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