Viability of Crushed and Diced Cartilage Grafts

Cakmak, Ozcan; Bircan, Sema; Büyüklü, Fuat; Tuncer, İlhan; Dal, Teoman; Özlüoğlu, Levent N.

doi:10.1001/archfaci.7.1.21

Cited by 98 publications

(81 citation statements)

References 19 publications

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“…Donor site morbidity is often not a concern for this material because nasal septal cartilage is usually within the surgical field in rhinoplasty. In addition, autogenous cartilage survives as living tissue and seldom undergoes resorption, as reported in clinical 4,5 and experimental 18,19 studies. Similarly, we found excellent viability for the cartilage groups throughout the study, with no evidence of resorption, as demonstrated by macroscopic and microscopic examinations, which showed normal cartilage architecture and normal chondrocytes.…”

mentioning

confidence: 84%

Comparison of AlloDerm, Fat, Fascia, Cartilage, and Dermal Grafts in Rabbits

Tarhan

Cakmak

Özdemir

et al. 2008

Archives of Facial Plastic Surgery

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To compare various graft materials in the rabbit model, including autologous cartilage, dermal tissue, fat, and AlloDerm (a cadaver-derived material).Methods: Twenty-five New Zealand white rabbits were used. Equally sized autogenous (fat, fascia, cartilage, and dermal) grafts and AlloDerm were implanted into subcutaneous dorsal pockets on the rabbits. Animals were killed 1, 2, 3, and 4 months after surgery. The grafts were examined microscopically for thickness, resorption, fibrosis, neovascularization, inflammation, eosinophilia, and the presence of multinucleated giant cells or microcysts. Results:The cartilage grafts revealed excellent viability with no resorption. The fascial grafts showed negli-gible volume loss. The dermal grafts developed epidermoid cysts. The AlloDerm grafts demonstrated graft thickening at 1 month and total resorption at 3 and 4 months. The fat grafts demonstrated 30% to 60% partial resorption. Conclusions:The major disadvantage of using an autogenous fat graft was partial resorption, whereas cyst formation was observed with dermal grafts. AlloDerm caused tissue reaction and resorption. The best graft material was cartilage, with a low absorption rate, good biocompatibility, and minimal tissue reaction or fibrosis, followed by fascia, with a minimal shrinkage capacity and tissue reaction.

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confidence: 84%

Comparison of AlloDerm, Fat, Fascia, Cartilage, and Dermal Grafts in Rabbits

Tarhan

Cakmak

Özdemir

et al. 2008

Archives of Facial Plastic Surgery

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“…11,25,26 In addition to these concerns, there is controversy regarding the short-and long-term effects of morselization on cartilage graft viability. Garg et al, 27 Cakmak and Buyuklu, 28 and Cakmak et al 29,30 believed that aggressive morselization decreases chondrocyte viability. Garg et al suggested that slightly and moderately crushed cartilages present uniform regions of viable and nonviable cells and thus could have more predictable graft survival.…”

Section: E9mentioning

confidence: 99%

Dorsal Nasal Augmentation: Is the Composite Graft Consisting of Conchal Cartilage and Retroauricular Fascia an Effective Option?

Varedi¹,

Bohluli

2015

Journal of Oral and Maxillofacial Surgery

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“…Each animal was separately anesthetized with halothane. The sedated animal was then further medicated with an intramuscular injection of 50 mg/kg of ketamine hydrochloride and 5 mg/kg of xylazine hydrochloride [3]. The skin of the sedated animals of group I was shaved at the ear pinna operative field and washed with povidone-iodine solution.…”

Section: Cartilage Harvest and Graft Preparationmentioning

confidence: 99%

“…They are commonly used for surgical correction of congenital, traumatic, aesthetic nasal abnormalities (rhinoplasty), tissue deficiency, foreshortening, and auricular reconstruction [1,2]. Cartilage graft survives as living tissue and does not stimulate an immune response; hence, problems with rejection, infection, and extrusion are rarely encountered with these grafts [3]. Cartilage graft may be used en-bloc as well as crushed or sliced (diced) [4].…”

Section: Introductionmentioning

confidence: 99%

Histological and immunohistochemical study on the survival of diced cartilage grafts wrapped in surgicel and fascia in albino rabbits

Allam

Sarhan

2014

The Egyptian Journal of Histology

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The specimens were prepared for histological and immunohistochemical study using glial fibrillary acidic protein to be examined by means of a light microscope. ResultsCartilage grafts wrapped in fascia showed the best survival, and cell viability was more or less similar to that of normal cartilage. They showed significant increase in the nuclear lacunar count, number of glial fibrillary acidic protein -positive chondrocytes, and in the pixel intensity of Mallory trichrome-stained sections. This was superior to those kept without wrapping and to those wrapped in surgicel. ConclusionDiced cartilage grafts wrapped with fascia demonstrated normal cartilage architecture with respect to chondrocyte viability and collagen and elastic content compared with cartilage grafts kept without wrapping or those wrapped in surgicel.

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Viability of Crushed and Diced Cartilage Grafts

Cited by 98 publications

References 19 publications

Comparison of AlloDerm, Fat, Fascia, Cartilage, and Dermal Grafts in Rabbits

Comparison of AlloDerm, Fat, Fascia, Cartilage, and Dermal Grafts in Rabbits

Dorsal Nasal Augmentation: Is the Composite Graft Consisting of Conchal Cartilage and Retroauricular Fascia an Effective Option?

Histological and immunohistochemical study on the survival of diced cartilage grafts wrapped in surgicel and fascia in albino rabbits

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