Vestibular Rehabilitation: Rationale and Indications

Kang, Christian M. Cabrera; Tusa, Ronald J.

doi:10.1055/s-0033-1354593

Cited by 23 publications

(10 citation statements)

References 39 publications

(52 reference statements)

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“…Additional therapeutic approaches include metoclopramide and antidepressant drugs (inhibitor of D1 receptor) that act on central function by reducing the sensation of vertigo, nausea, and gastrointestinal symptoms [146]. For chronic dizziness, specific rehabilitation treatments can be used to favor central vestibular compensation and restore normal balance function [147]. …”

Section: Inner Ear Involvement In Autoimmune Diseasesmentioning

confidence: 99%

Audiovestibular Symptoms in Systemic Autoimmune Diseases

Ralli

D’Aguanno

Stadio

et al. 2018

Journal of Immunology Research

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Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss is the most common audiovestibular symptom associated with systemic autoimmune diseases, although conductive hearing impairment may also be present. Hearing loss may present in a sudden, slowly, rapidly progressive or fluctuating form, and is mostly bilateral and asymmetric. Hearing loss shows a good response to corticosteroid therapy that may lead to near-complete hearing restoration. Vestibular symptoms, tinnitus, and aural fullness can be found in patients with systemic autoimmune diseases; they often mimic primary inner ear disorders such as Menière's disease and mainly affect both ears simultaneously. Awareness of inner ear involvement in systemic autoimmune diseases is essential for the good response shown to appropriate treatment. However, it is often misdiagnosed due to variable clinical presentation, limited knowledge, sparse evidence, and lack of specific diagnostic tests. The aim of this review is to analyse available evidence, often only reported in the form of case reports due to the rarity of some of these conditions, of the different clinical presentations of audiological and vestibular symptoms in systemic autoimmune diseases.

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Section: Inner Ear Involvement In Autoimmune Diseasesmentioning

confidence: 99%

Audiovestibular Symptoms in Systemic Autoimmune Diseases

Ralli

D’Aguanno

Stadio

et al. 2018

Journal of Immunology Research

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“…Current knowledge advises the initiation of vestibular rehabilitation (VR) as soon as possible after an acute vestibular syndrome ( 29 , 30 ). VR works as a catalyzer and enhancer of central compensation on the basis of three principles: adaptation (rearrangement of VOR networking), substitution (strengthening of non-vestibular components of balance), and habituation (increase of sensory thresholds).…”

Section: Management Of Elderly Patients With Dizzinessmentioning

confidence: 99%

Vertigo and Dizziness in the Elderly

2015

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The prevalence of vertigo and dizziness in people aged more than 60 years reaches 30%, and due to aging of world population, the number of patients is rapidly increasing. The presence of dizziness in the elderly is a strong predictor of falls, which is the leading cause of accidental death in people older than 65 years. Balance disorders in the elderly constitute a major public health problem, and require an adequate diagnosis and management by trained physicians. In the elderly, common causes of vertigo may manifest differently, as patients tend to report less rotatory vertigo and more non-specific dizziness and instability than younger patients, making diagnosis more complex. In this mini review, age-related degenerative processes that affect balance are presented. Diagnostic and therapeutic approaches oriented to the specific impaired system, including visual, proprioceptive, and vestibular pathways, are proposed. In addition, presbystasis – the loss of vestibular and balance functions associated with aging – benign paroxysmal positional vertigo, and stroke (in acute syndromes) should always be considered.

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“…In addition to aging, hair cells are also susceptible to injury from trauma and aminoglycoside ototoxicity, while supporting cells are less vulnerable (Lee et al, 2013). Since these factors also contribute to BPPV, protecting or regenerating sensory hair cells are possible strategies to treat vestibular dysfunction (Cabrera Kang and Tusa, 2013). Indeed, adenoviral delivery of Atoh1 into the supporting cells of the inner ear has recently been approved for human clinical trials to treat auditory and balance disorders (Géléoc and Holt, 2014).…”

Section: Degeneration and Regeneration Of Otoconiamentioning

confidence: 99%

Mechanisms of otoconia and otolith development

Lundberg

Thiessen

et al. 2014

Developmental Dynamics

128

134

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Otoconia are bio-crystals which couple mechanic forces to the sensory hair cells in the utricle and saccule, a process essential for us to sense linear acceleration and gravity for the purpose of maintaining bodily balance. In fish, structurally similar bio-crystals called otoliths mediate both balance and hearing. Otoconia abnormalities are common and can cause vertigo and imbalance in humans. However, the molecular etiology of these illnesses is unknown, as investigators have only begun to identify genes important for otoconia formation in recent years. To date, in-depth studies of selected mouse otoconial proteins have been performed, and about 75 zebrafish genes have been identified to be important for otolith development. This review will summarize recent findings as well as compare otoconia and otolith development. It will provide an updated brief review of otoconial proteins along with an overview of the cells and cellular processes involved. While continued efforts are needed to thoroughly understand the molecular mechanisms underlying otoconia and otolith development, it is clear that the process involves a series of temporally and spatially specific events that are tightly coordinated by numerous proteins. Such knowledge will serve as the foundation to uncover the molecular causes of human otoconia-related disorders.

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Vestibular Rehabilitation: Rationale and Indications

Cited by 23 publications

References 39 publications

Audiovestibular Symptoms in Systemic Autoimmune Diseases

Audiovestibular Symptoms in Systemic Autoimmune Diseases

Vertigo and Dizziness in the Elderly

Mechanisms of otoconia and otolith development

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