Vestibular and cochlear nerve enhancement on MRI and its correlation with vestibulocochlear functional deficits in patients with Ramsay Hunt syndrome

Takahashi, Mika; Sato, Go; Toda, Naoki; Azuma, Takehiko; Nakamura, Katsuhiko; Iwasaki, Hidetaka; Miyoshi, Hitomi; Matsuda, Kazunori; Kitamura, Yoshiaki; Abe, Kōji; Takao, Shoichiro; Harada, Masafumi; Takeda, Noriaki

doi:10.1016/j.anl.2020.08.027

Cited by 8 publications

(11 citation statements)

References 18 publications

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“…15 This pattern is distinct from reports of such radiographic abnormalities being restricted to the vestibular/vestibulocochlear nerve. 1 Although this is a small study, the findings have several clinical implications. First, it provides a rationale for a future prospective study of whether brainstem MRI can help distinguish VN and HZO.…”

Section: Discussionmentioning

confidence: 83%

“…15 This pattern is distinct from reports of such radiographic abnormalities being restricted to the vestibular/vestibulocochlear nerve. 1…”

Section: Discussionmentioning

confidence: 99%

“…5 Evidence of inflammation (neuritis) within the auditory and vestibular nerves and the labyrinth has been noted on postmortem examinations of patients with HZO 6 and extensively reported in MRI studies. 1 Using contemporary vestibular testing, Eduardo Martin-Sanz et al 7 have reported that HZO is associated with more severe symptomatology and poorer recovery in comparison with the more prevalent vestibular neuritis (VN); they concluded that other mechanisms besides purely peripheral neural inflammation could be involved.…”

Section: Introductionmentioning

confidence: 99%

“…HZO is believed to be caused by reactivation of latent varicella zoster virus (VZV) in the geniculate ganglion, which may affect all the nerve trunks within the internal auditory canal. 1 Many neurologic complications of VZV reactivation can occur (including meningoencephalitis, neuromyelitis, cerebellitis, vasculitis, and cranial neuritis) in rare cases even without the skin rash.…”

Section: Introductionmentioning

confidence: 99%

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Vestibular Nucleus Involvement in Patients With Acute Vertigo Due to Herpes Zoster Oticus or Vestibular Neuritis

et al. 2023

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Introduction:Herpes zoster oticus (HZO) typically provokes vestibular symptoms and is traditionally viewed as a cranial nerve equivalent of shingles, but in contrast to vestibular neuritis (VN), it is unclear whether the pathology of HZO is limited to the vestibular nerve (neuritis) or can also involve the brainstem (nucleitis). Methods: We retrospectively compared brain MRIs of HZO patients with those of patients with vestibular neuritis (VN) to study radiological changes in the brainstem. Results: Five out of 10 HZO patients showed signal abnormalities in the vestibular nuclei, which lie in multiple vascular territories, whereas no VN patients exhibited such findings. Conclusion: HZO may at least in part reflect vestibular nucleitis, as opposed to a pure neuritis.

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Section: Discussionmentioning

confidence: 83%

“…15 This pattern is distinct from reports of such radiographic abnormalities being restricted to the vestibular/vestibulocochlear nerve. 1…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Vestibular Nucleus Involvement in Patients With Acute Vertigo Due to Herpes Zoster Oticus or Vestibular Neuritis

et al. 2023

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“…In addition, it is not known whether enhancement of the Scarpa's ganglion region directly translates to clinical symptoms or should be considered pathologic. [7][8][9][10] This study set out to is to address this gap in knowledge by assessing the prevalence of enhancement at Scarpa's ganglion and evaluating whether it bears clinical relevance. To accomplish this, high-resolution MRI images were reviewed for Scarpa's ganglion enhancement, and assessed to determine if these findings correlated to hearing loss, vestibular symptoms, or tinnitus.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Scarpa’s ganglion enhancement on high-resolution MRI imaging

Siminski,

Benson,

Carlson

et al. 2024

Neuroradiol J

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Background and Purpose The vestibular ganglion, or Scarpa’s ganglion, is a cluster of afferent vestibular neurons within the internal auditory canal (IAC). There is minimal literature describing enhancement of this region on magnetic resonance imaging (MRI) and its correlation to clinical symptoms. Here, we sought to find the prevalence of enhancement at Scarpa’s ganglion, and determine whether such enhancement correlates with demographics or clinical symptoms. Materials and Methods A retrospective review was performed of consecutive patients with an MRI of the IAC between 3/1/2021 and 5/20/2021. Two neuroradiologists independently reviewed for T1 and FLAIR enhancement of the Scarpa’s ganglion on post-contrast fat-saturated T1 and post-contrast FLAIR images. Discrepancies were agreed upon by consensus. Clinical variables (hearing loss, vestibular symptoms, tinnitus, and MRI indication) were gathered from a retrospective chart review. Results Eighty-nine patients were included (51 female); the mean age was 58 (range 19–85). The most common MRI indication was hearing loss ( n = 53). FLAIR enhancement was present on the right in 7 patients, on the left in 7 patients, and bilaterally in 6 patients. No enhancement was seen on post-contrast T1 images. There was no statistically significant correlation between consensus FLAIR on at least one side and age ( p = .74), gender ( p = .29), hearing loss ( p = .32), hearing loss side ( p = .39), type of hearing loss ( p = .87), vestibular symptoms ( p = .71), or tinnitus ( p = .81). Conclusions Enhancement is present in the minority of patients on post-contrast FLAIR images. If seen, it should be considered an uncommon but not unexpected finding with no clinical significance.

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Vestibular mapping in Ramsay-Hunt syndrome and idiopathic sudden sensorineural hearing loss

Hong

Lee

Kim

2023

Eur Arch Otorhinolaryngol

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Vestibular and cochlear nerve enhancement on MRI and its correlation with vestibulocochlear functional deficits in patients with Ramsay Hunt syndrome

Cited by 8 publications

References 18 publications

Vestibular Nucleus Involvement in Patients With Acute Vertigo Due to Herpes Zoster Oticus or Vestibular Neuritis

Vestibular Nucleus Involvement in Patients With Acute Vertigo Due to Herpes Zoster Oticus or Vestibular Neuritis

Prevalence of Scarpa’s ganglion enhancement on high-resolution MRI imaging

Vestibular mapping in Ramsay-Hunt syndrome and idiopathic sudden sensorineural hearing loss

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