Vessel Diameter: A Key Factor Influencing Fractional Flow Reserve

Abstract

In this study, we explored the effect of vessel diameter of coronary artery where the stenosis is located on FFR at the same vascular level. This study is divided into two parts: clinical statistics and numerical simulation. In the clinical statistics section, we compared the blood vessel diameter where the stenosis is located of the ischemic group and the non-ischemic group. In the numerical simulation section, we further explored the effect of diameter on myocardial ischemia by using an ideal model. With the increase in stenosis rate and stenotic vessel flow, the FFR rate of the larger stenotic vessels was higher than that of smaller stenotic vessels. The larger blood vessels are more prone to ischemia when coronary artery stenosis occurs.